Exoderil - instructions for use, analogs, reviews and release forms (cream or ointment, 1% solution) of the drug for the treatment of nail fungus and other mycoses in adults, children and pregnancy

In this article, you can read the instructions for using the drug Exodermil. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of experts on the use of Exoderil in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Exoderil in the presence of existing structural analogues. Use for the treatment of nail fungus and other mycosis skin and skin folds in adults, children, as well as during pregnancy and lactation.

Exodermil - an antifungal agent for external use from the group of allylamines. The mechanism of action is associated with inhibition of the synthesis of ergosterol, while naftifin (the active substance of the drug Exoderyl) affects squalene epoxidase.

The drug is active against dermatophytes Trichophyton, Epidermophyton, Microsporum, yeast (Candida), mold fungi (Aspergillus) and other fungi (Sporotrix schenckii). In vitro in respect of dermatophytes and aspergillus, naphthyfine acts fungicidally. With regard to yeast fungi shows fungicidal and fungistatic activity, depending on the strain of the microorganism. The drug has antibacterial action against gram-positive and gram-negative microorganisms.

In clinical conditions, it was found that the drug has an anti-inflammatory effect that promotes the rapid disappearance of inflammation symptoms, especially itching.

As Exodermil rapidly penetrates the skin, creating stable antifungal concentrations in its different layers, it is possible to use it locally once a day.

Pharmacokinetics

With external use, Exoderyl penetrates well into various layers of the skin, reaching concentrations sufficient for antifungal action.After application, only 6% of the active substance is exposed to the skin of the systemic absorption cream. The absorbed amount is partially metabolized and excreted in the urine and bile.

Indications

• mycosis of the skin and skin folds;
• interdigital mycoses (brushes, feet);
• onychomycosis;
• candidiasis of the skin;
• pityriasis lichen;
• inflammatory dermatomycosis (with or without accompanying itching).

Forms of release

Cream or still incorrectly called ointment for external use.

Solution for external use 1%.

Instructions for use and usage diagram

Exoderyl should be applied to the affected surface of the skin and adjacent areas once a day, after thorough cleaning and drying, taking approximately 1 cm of healthy skin at the edges of the affected area.

Duration of treatment for dermatomycosis - 2-4 weeks (if necessary - up to 8 weeks), with candidiasis - 4 weeks, with onychomycosis the drug should be applied 2 times a day for up to 6 months.

With onychomycosis before the first application of the solution, it is necessary to remove the affected part of the nail as much as possible with scissors and a nail file.

To prevent recurrence of infection, therapy should be given for at least 2 weeks after the clinicalcure.

Side effect

• dry skin;
• hyperemia;
• burning.

Contraindications

• pregnancy (safety and efficacy not determined);
• lactation period (safety and efficacy not determined);
• hypersensitivity to naphthyfine and benzyl alcohol (for cream) or propylene glycol (for solution).

The drug should not be applied to the wound surface.

Application in pregnancy and lactation

Contraindicated the use of the drug Exodermil during pregnancy and lactation (safety and efficacy not determined).

special instructions

Avoid contact with the eyes and open wounds.

Drug Interactions

There was no drug interaction between the drug Exoderyl and other drugs.

Analogues of the drug Exoderyl

Structural analogues for the active ingredient do not have Exoderyl.

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