Bronchobos - instructions for use, analogs, testimonials and release forms (125 mg syrup - 2.5% and 250 mg - 5%, capsules or tablets 375 mg) of a cough drug with viscous sputum for bronchitis, tracheitis in adults, children and during pregnancy. Composition

In this article, you can read the instructions for using the drug Bronhobos. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Bronhobos in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Bronhobos in the presence of existing structural analogues. Use for treatment of cough with viscous sputum in bronchitis, laryngitis, tracheitis in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Bronhobos - mucolytic and expectorant drug.

Mucolytic and expectorant action is due to the activation of sialic transferase - the enzyme of goblet cells of bronchial mucosa. Normalizes the quantitative ratio of acidic and neutral sialomucins to bronchial secretions.

Reduces the viscosity of the bronchial secretion and the discharge from the paranasal sinuses, facilitates the passage of sputum and mucus, reduces cough. Promotes regeneration of the mucous membrane, normalizes its structure, activates the activity of the ciliary epithelium. It restores immunoglobulin IgA secretion (specific defense) and the amount of sulfhydryl groups of mucus components (nonspecific defense), improves mucociliary clearance.

Composition

Carbocysteine ​​+ excipients.

Pharmacokinetics

Carbocysteine ​​is rapidly absorbed after oral administration. Bioavailability is low (less than 10% of the dose taken). Metabolised in the liver (has the effect of "first pass" through the liver). It is excreted mainly by the kidneys, partly unchanged, partly in the form of metabolites.

Indications

• acute and chronic bronchopulmonary diseases, accompanied by the formation of viscous, hard to separate sputum (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectatic disease);
• inflammatory diseases of the middle ear (otitis media);
• inflammatory diseases of the nose and its adnexal sinuses (rhinitis, sinusitis or sinusitis);
• preparation for bronchoscopy and / or bronchography.

Forms of release

Syrup 2.5% or 125 mg.

Syrup 5% or 250 mg.

Capsules 375 mg (sometimes mistakenly called pills).

Instructions for use and dosage

The drug is prescribed inside, after eating.

Capsules

Adults and adolescents over 15 years: 750 mg (2 capsules) 3 times a day. After achieving the therapeutic effect, the daily dose is reduced to 1.5 g: 750 mg (2 capsules) 2 times a day. Treatment should not be continued for more than 8-10 days without consulting a physician.

Syrup

To dispense the syrup, a measuring spoon with a volume of 5 ml, graduated by 2.5 ml should be used.

1 measuring spoonful of syrup 5% (5 ml) = 250 mg carbocysteine

1 measuring spoon of syrup 2.5% (5 ml) = 125 mg of carbocysteine

Adults: 15 ml each (3 scoops) 5% syrup 3 times a day.

Children aged 3-6 years: 5 ml (1 measuring spoon) 2.5% syrup 2-4 times a day.

Children over the age of 6 years: 5-10 ml (1-2 scoops) 2.5% syrup 3 times a day.

Side effect

• nausea, vomiting;
• diarrhea;
• pain in epigastrium;
• gastrointestinal bleeding;
• itching;
• hives;
• exanthema;
• angioedema;
• dizziness;
• weakness;
• malaise;
• In patients with bronchial asthma and in elderly patients, airway obstruction may occur.

Contraindications

• hypersensitivity to carbocysteine ​​and other components of the drug;
• peptic ulcer of the stomach and duodenum in the phase of exacerbation;
• chronic glomerulonephritis in the phase of exacerbation;
• cystitis;
• liver disease (for taking syrup);
• alcoholism (for taking syrup);
• epilepsy (for taking syrup);
• trauma or brain disease (for taking syrup);
• pregnancy;
• lactation (breastfeeding);
• children under 3 years of age (for taking syrup 2.5%);
• children under 15 years (for taking capsules and syrup 5%).

Carefully:

• with chronic glomerulonephritis (in the anamnesis);
• peptic ulcer of stomach and duodenum (in the anamnesis);
• in 2-3 trimesters of pregnancy and during breastfeeding.

Application in pregnancy and lactation

The drug Bronhobos in the form of syrup is contraindicated for use in pregnancy and lactation (breastfeeding).

The drug in the form of capsules is prescribed in the second and third trimester of pregnancy only if the intended benefit to the mother exceeds the potential risk to the fetus.

If it is necessary to prescribe the drug during lactation, the question of stopping breastfeeding should be solved.

Use in children

Contraindicated in children under 3 years of age (for taking syrup 2.5%); children under the age of 15 (for taking capsules and syrup 5%).

special instructions

In patients with peptic ulcer in history, the dose of the drug should be reduced. Treatment can be combined with physiotherapy procedures.

The content of ethanol (alcohol) in the syrup is 125 mg / 5 ml, i.e. 125 mg of ethanol per measuring spoon.

It is not recommended to use the drug Bronhobos with a dry cough (does not prevent cough, and displays phlegm).

Impact on the ability to drive vehicles and manage mechanisms

The effect of the drug on the ability to drive vehicles and perform work that requires a high concentration of attention and speed of psychomotor reactions has not been studied.The drug Bronhobos in the form of a syrup contains alcohol, which must be taken into account when driving a vehicle.

Drug Interactions

Increases the effectiveness of glucocorticoid (mutually) and antibacterial therapy of infectious and inflammatory diseases of the upper and lower respiratory tract.

Potentsiruet broncholytic effect of theophylline.

Carbocisteine ​​activity is weakened by antitussive and atropine-like agents.

Because of the ethanol content, Bronhobos in the form of a syrup is prescribed with caution:

• with preparations that cause adverse reactions (fever, redness of the skin, vomiting, tachycardia) with simultaneous reception with alcoholic beverages: disulfiram, cefamandol, cefoperazone, latamoxef (cephalosporin antibiotics), chloramphenicol (phenylic antibiotic), chlorpropamide, glibenclamide, glipizide, tolbutamide (hypoglycemic sulfonylurea derivative), griseofulvin (antifungal agent), nitro-5-imidazoles (metronidazole, ornidazole, secnidazole, tinidazole), ketoconazole, procarbazine (cytostatic);
• with drugs that depress the central nervous system.

Analogues of the drug Bronchobos

Structural analogs for the active substance:

• Bronkatar;
• Carbocysteine;
• Libexin Muko;
• Mukodin;
• Mukoprint;
• Mucosol;
• Fluidite.

Analogues on the pharmacological group (secretolytics and mucolytics):

• Ambrogen;
• Ambroxol;
• Amtersol;
• Ascoril;
• Acetylcysteine;
• ATSTS;
• ATSTS Long;
• Bromhexine;
• Bromhexine for children;
• Bronchicum;
• Bronchicum inhalate;
• Bronchicum cough lozenges;
• Bronchipret;
• Bronchorus;
• Bronchostop;
• Gedelix;
• GeloMirtol;
• Glycyrs;
• Chest fee;
• Doctor IOM;
• Dr. Theiss;
• Zedex;
• Insty;
• Carbocysteine;
• Kodelak Broncho;
• Broncho's Witchcraft;
• Coldrex Bronho;
• Cofisma;
• Lazolvan;
• Libexin Muko;
• Linkas;
• Mistabrone;
• Mukaltin;
• Mucofitin;
• Expectorant collection;
• Pectusin;
• Pertussin;
• Prospan;
• Pulmonizing;
• Reglis;
• Sinupret;
• Mixture for inhalation;
• Solutan;
• Stoptussin;
• Thermopsol tablets for cough;
• Terpin hydrate;
• Travisil;
• Tussamag;
• Tussin;
• Fervex from coughing;
• Flavamed;
• Flavamed forte;
• Fluimucil;
• Fluviert;
• Fluidite;
• Haliksol;
• Eucatol;
• Elmucin;
• Erdomed;
• Erdosteine.

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