Ekofuril - instructions for use, reviews, analogs and forms of release (capsules or tablets of 100 mg and 200 mg) of the drug for the treatment of infectious diarrhea or diarrhea, colitis and gastroenteritis in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Ecofuryl. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Ekofuril in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Ekofuril in the presence of existing structural analogues. Use to treat infectious diarrhea or diarrhea, colitis and gastroenteritis in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Ecofuryl - a broad-spectrum antimicrobial agent - a derivative of 5-nitrofuran for the treatment of gastrointestinal infections.

Nifuroxazide (the active substance of the preparation Ekofuril) blocks the activity of dehydrogenases and depresses the respiratory chains, the cycle of tricarboxylic acids and other biochemical reactions in the bacterial cell. It destroys the membranes of sensitive bacteria, reduces the production of toxins by microorganisms. Activates immunity, increases the activity of phagocytes and the complement titer.

Effective against gram-positive microorganisms: Staphylococcus spp. (Staphylococcus aureus), Streptococcus spp. (streptococcus); Gram-negative microorganisms: Salmonella spp. (salmonella), Klebsiella spp. (Klebsiella), Enterobacter spp., Escherichia coli (Escherichia coli), Shigella spp. (Shigella), Proteus spp. (proteus), Haemophilus influenzae, Campilobacter spp., Edwarsiella spp., Citrobacter spp., Vibrio cholerae, Yersinia enterocolitica.

Ecofuril has no effect on the state of normal microflora of the human intestine. With acute bacterial diarrhea, eubiosis of the intestine is restored. When infected with enterotrophic viruses prevents the development of bacterial superinfection.

Composition

Nifuroxazide + excipients.

Pharmacokinetics

After oral administration, Nifuroxazide is practically not absorbed from the digestive tract and does not have a systemic effect.Antibacterial activity against sensitive species of bacteria manifests only in the lumen of the intestine. In unchanged form is excreted by the intestine. The speed of elimination depends on the dose of the drug and the motility of the gastrointestinal tract.

Indications

• acute and chronic diarrhea or diarrhea of ​​infectious genesis (without signs of helminthic invasion) with symptoms of poisoning and intoxication;
• chronic colitis and enterocolitis.

Forms of release

Capsules 100 mg and 200 mg.

Other dosage forms, whether tablets, solution or suspension at the time of publication of the drug in the Directory did not exist.

Instructions for use and dosage

The drug is taken orally. Eating does not affect the effect of the drug (you can take both before and after meals).

Adults and children over 7 years of age are prescribed 2 capsules 100 mg or 1 capsule 200 mg 4 times a day (800 mg per day).

Children aged 3-7 years are prescribed 2 capsules 100 mg or 1 capsule 200 mg 3 times a day (600 mg per day).

The duration of therapy with Ecofuril is no more than 7 days.

Side effect

• allergic reactions.

Contraindications

• hypersensitivity to nifuroxazide, other components of the drug, other 5-nitrofuran derivatives;
• deficiency of sugar / isomaltase, intolerance to fructose, glucose-galactose malabsorption;
• Children under 3 years old (for this dosage form).

Application in pregnancy and lactation

There are no data on the adverse effects of Eco-fouler on the fetus during pregnancy. If necessary, with caution, the drug can be given to pregnant women and women breastfeeding.

Use in children

Contraindicated use of the drug in childhood to 3 years, including infants and newborns (for this dosage form).

special instructions

In the treatment of diarrhea concomitantly with therapy with Ecofuril, rehydration therapy (oral or intravenous) should be performed in accordance with the patient's condition and duration of diarrhea.

During the treatment with Ecofuril, alcohol is not allowed.

Impact on the ability to drive vehicles and manage mechanisms

The drug does not adversely affect the ability to drive vehicles and / or other mechanisms.

Drug Interactions

No data on the interaction of nifuroxazide with other drugs have been published.

During treatment with Ecofuril, simultaneous oral administration should be avoided due to the strong adsorption properties of the drug.

Analogues of the drug Ekofuril

Structural analogs for the active substance:

• Adisord;
• Mirofuril;
• Nifuroxazide;
• Nifuroxazide Richter;
• Stoppier;
• Elufour;
• Enterofuryl;
• Ersefuril.

Analogues on the curative effect (funds for the treatment of diarrhea of ​​infectious origin):

• Amoxicillin;
• Ampicillin;
• Acipol;
• Bactisubtil;
• Biseptol;
• Bifidumbacterin;
• Gentamicin;
• Diar;
• Doxycycline hydrochloride;
• Dufalac;
• Carbopect;
• Levomycetin;
• Macropean;
• Megion;
• Mezim;
• Mezim forte;
• Metrogil;
• Microfleks;
• Nagypol;
• Neosmectin;
• Nolycin;
• Norbaktin;
• Ospamox;
• Pangrol;
• Pefloxacin;
• Piobacteriophage complex;
• Polybacterin;
• Probiophore;
• Smecta;
• Sulgin;
• Sulfadimethoxin;
• Trimezol;
• Activated carbon;
• STI Filter;
• Forcef;
• Phthalazole;
• Furazolidone;
• Chlosol;
• Tzedek;
• Ceftidine;
• Ceftriabal;
• Ceftriaxone;
• Ciprinol;
• Tsiprolet;
• Ciprofloxacin;
• Tsifran;
• Entereroz;
• Enterosgel;
• Hermitage;
• Utibid.

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