Stellanin - instructions for use, analogs, reviews and release forms (ointment 3% PEG, drops or solution for ingestion and external use) drugs for the treatment of pressure sores, hemorrhoids, burns in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Stellanin. There are reviews of visitors to the site - consumers of this medication, as well as opinions of specialists in the use of Stellanin in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Stellanin with available structural analogues.Use for the treatment of pressure sores, hemorrhoids, burns and trophic ulcers in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Stellanin - The mechanism of pharmacological activity of the drug is the direct regenerative action of 1,3-diethylbenzimidazolium on damaged skin. Active iodine, which is part of the preparation, inactivates bacterial wall proteins and enzyme proteins of bacteria, thus having a bactericidal effect.

Stellanin protects the wound surface from infections, suppresses the course of the infectious process and promotes healing.

The drug has a broad spectrum of antibacterial activity.

Along with antibacterial and anti-inflammatory effects, ointment has a high osmotic potential, which is especially important in the treatment of purulent wounds, t. facilitates the evacuation of a wound defect purulent discharge.

To Stellanin, Staphylococcus aureus (Staphylococcus), Clostridium dificille, Pseudomonas aeruginosa, Klebsiella pneumoniae (Klebsiella), Streptococcus viridans (Streptococcus), Streptococcus haemolyticus, Proteus mirabilis (Proteus), Escherichia coli (E. coli), Neisseria spp .; fungi Candida albicans (candida) and some other pathogens.

Composition

Diethylbenzimidazolium triiodide + auxiliary substances.

Pharmacokinetics

Ointment

Systemic absorption of the active substance is absent even with damaged skin, however, therapeutic concentrations of the drug are present in the wound.

Drops for oral and topical application

When administered orally, the time to achieve Cmax Iodine in plasma averages 2.05 hours. The Cmax value of iodide in plasma is on average 2.80 μg / ml.

Indications

For ointment

• trophic ulcers of the lower extremities;
• pressure sores;
• hemorrhoids;
• burns 1 and 2 degrees;
• abrasions, cuts, scratches, cracks, brushing, incl. after insect bites;
• additional treatment of aseptic postoperative wounds (after excision, coagulation, episiotomy, treatment of skin cracks, wounds and sutures);
• treatment of acute purulent processes (wounds) of skin and soft tissues (furuncles, carbuncles, hydradenitis, phlegmon, abscesses);
• acceleration of engraftment of the skin graft.

Drops for oral and topical application

• chronic tonsillitis;
• a pharyngitis in a stage of an exacerbation.

Forms of release

Drops for oral administration and topical application (in 25 ml dropper bottles).

Ointment for external use 3% (Stellanin PEG in tubes of 20 g).

Other drug dosage forms, whether it is a solution, gel or cream, do not exist.

Instructions for use and how to use them

Ointment

The drug is applied to the damaged skin surface so that the skin area is covered with the drug completely. The duration and frequency of application depends on the severity of the disease and the localization of the process. The daily dose should not exceed 10 g. It is possible to use occlusive dressings and plaster.

In the treatment of granulating burns, wounds and trophic ulcers with mild exudation, the preparation is applied uniformly with a thickness of 1-1.5 mm so that the entire affected area is covered with ointment and a sterile gauze bandage is applied. Change dressings are carried out 1 time in 1-2 days in the treatment of burns and 1-2 times a day in the treatment of wounds and trophic ulcers. With the open method of treating burns, the drug is applied 1-2 times a day. The duration of treatment is determined by the dynamics of epithelialization of wounds.

For minor skin lesions (abrasions, cuts, scratches, cracks, scratching), the drug is applied a thin layer on the affected surface 2 times a day.

Drops for oral and topical application

Locally or inward.

Strictly on an empty stomach, no less than 30 minutes before a meal.

1 ml (50 drops containing 40 mg of 1,3-diethylbenzimidazolium triiodide) of the drug, diluted in 50 ml (1/4 cup) of boiled water at room temperature in a glass bowl 2-3 times a day inside. Before ingestion, the throat should be rinsed with a solution of the drug.

The maximum daily dose is 3 ml (120 mg of 1,3-diethylbenzimidazolium triiodide). The course of treatment is 5-10 days.

Side effect

• allergic reactions (itching, skin hyperemia);
• eosinophilia;
• tachycardia;
• nervousness;
• insomnia.

Contraindications

• thyrotoxicosis;
• adenoma of the thyroid gland;
• acute renal insufficiency;
• simultaneous therapy with radioactive iodine;
• children under 18;
• 1 trimester of pregnancy;
• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

The drug Stellanin is contraindicated in the first trimester of pregnancy.

With caution: 2 and 3 trimesters of pregnancy, lactation.

Use in children

Contraindicated in children and adolescents under the age of 18 years.

special instructions

With caution use Stellanin in chronic kidney failure, in the 2nd and 3rd trimesters of pregnancy, during lactation.

Ointment can not be applied to mucous membranes.

If the product gets into eyes or mucous membranes, rinse with warm water.

Applying stellanin ointment from hemorrhoids, the following effects are achieved:

• vascular growth of vegf-A and vegf-B is stimulated, which provides elimination of the existing vascular pathology. As a result, the walls of the blood vessels return elasticity and strength;
• stellanin almost 8 times accelerates the process of dividing tissue cells, thereby healing of wounds occurs faster. Thanks to the ongoing regenerative processes, the bundles supporting the nodes restore their original properties;
• inflammatory processes are blocked, and pain syndrome is eliminated;
• Destroy pathogenic microorganisms that cause the appearance of skin infections.

Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity and the bactericidal action of the drug may decrease.

Drug Interactions

Ointment

Do not use the drug in combination with other antiseptic agents containing mercury, oxidants, alkalis and cationic surfactants.

In the presence of blood, the bactericidal action of the drug may decrease.

Drops for oral and topical application

Stellanin is not recommended to be taken concomitantly with other medications.

The interval between taking Stellanin and other drugs should be at least 30 minutes.

Analogues of the drug Stellanin

Structural analogs for the active substance:

• 1,3-Diethylbenzimidazolium triiodide;
• Stellanin PEG.

Analogues for the pharmacological group (regenerants and reparants):

• D Panthenol;
• Adelon;
• Actovegin;
• Actovegin concentrate;
• Apilak;
• Aurobin;
• Bepanten;
• Bepanten plus;
• Betamecil ointment eye 2%;
• Vinilin (Shostakovsky's Balm);
• Gel for normalization of vaginal microflora Floragin Gel;
• Gebreolone;
• Gepalpan;
• Hepatrombin;
• Gialgan Phidias;
• Hyposol;
• Humisol;
• D Panthenol;
• Dexpanthenol;
• Depanthol;
• Healthy eyes;
• Intragel;
• Kontraktubeks;
• Korneregel;
• Xymedon;
• Curious;
• Levomekol;
• Liniment balsamic (according to Vishnevsky);
• Methyluracil;
• Morale plus;
• Sodium deoxyribonucleate;
• Sea buckthorn oil;
• Olesesin;
• Panagen;
• Panthenol;
• Pantenolspray;
• Pantoderm;
• Pentoxyl;
• Piolizin;
• Polyvinox;
• Simpletons;
• Relief Ultra;
• Reparff;
• Retinalamine;
• Rumalon;
• Solcoseryl;
• Solcoseryl dental adhesive paste;
• Stellanin PEG;
• Stisamet;
• Strix;
• Tyqveol;
• Ulzep;
• Fitostimulin;
• Fusimet;
• Ebermin;
• Eplan;
• The index.

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