Rengalin - instructions for use, analogs, reviews and release forms (tablets for resorption, solution or syrup) antitussive drug for cough, including dry in adults, children and during pregnancy. Composition
In this article, you can read the instructions for using the drug Rengalin. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Rengalin in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Rengalin with existing structural analogues. Use for the treatment of cough, including dry with bronchitis,pneumonia and other infectious and allergic diseases accompanied by coughing, in adults, children, as well as during pregnancy and lactation. Composition of antitussive drug.
Rengalin - experimentally shown that the components of the drug activity is modified ligand-receptor interaction of endogenous regulators of the corresponding receptors: morphine antibody - to opiate receptors; antibodies to histamine - with H1-histamine receptors; antibodies to bradykinin - with B1-receptors of bradykinin; while the combined use of components leads to an increase in the antitussive effect.
Furthermore antitussive action, due to the complex preparation of its constituent components having anti-inflammatory, anti-edema, anti-allergic, antispasmodic (antibody to histamine, bradykinin antibodies) and analgesic effect (antibody to morphine).
Complex preparation Rengalin through modification-dependent activation of histamine H1-receptors and bradykinin-B2-dependent activation of receptors selectively reduces the excitability of the cough center of the medulla oblongata, inhibits central links cough reflex.Inhibiting the centers of pain sensitivity in the thalamus, blocks transmission of pain impulses to the cerebral cortex. Inhibits the flow of painful impulses from the periphery due to a decrease in the release of tissue and plasma algogens (histamine, bradykinin, prostaglandins, etc.). Unlike narcotic analgesics does not cause respiratory depression, drug dependence, does not possess narcogenic and hypnotic effects.
It alleviates the manifestations of acute pharyngitis, laryngitis and bronchitis, reducing bronchospasm. It relieves systemic and local symptoms of allergic reactions by influencing the synthesis and release of histamine and bradykinin from mast cells.
Composition
Antibodies to bradykinin + Antibodies to histamine + Antibodies to morphine + excipients.
Antibodies are applied to lactose in the form of a mixture of three active hydroalcoholic dilutions of the substance diluted in 100 to 12 degrees, 100 to 30 degrees, 100 to 200 times, therefore, it is possible to call Rengalin a homeopathic remedy.
Pharmacokinetics
The sensitivity of modern physicochemical methods of analysis (gas-liquid chromatography, high-performance liquid chromatography,chromatography-mass spectrometry) does not allow to estimate the content of ultra-small doses of antibodies in biological fluids, organs and tissues, which makes it technically impossible to study the pharmacokinetics of the Rengalin preparation.
Indications
- acute and chronic diseases of the respiratory tract, accompanied by cough and bronchospasm;
- productive and nonproductive cough with influenza and acute respiratory viral infection, acute pharyngitis, laryngotracheitis, acute obstructive laryngitis, chronic bronchitis and other infectious-inflammatory and allergic diseases of the upper and lower respiratory tract.
Forms of release
Lozenges.
Solution for oral administration (sometimes mistakenly called syrup).
Instructions for use and reception scheme
Inside, out of the reception of food.
At one time - 1 tablet (keep in your mouth until completely dissolved) or 1-2 teaspoons (5-10 ml). It is advisable to keep the solution in the mouth before swallowing for maximum effect of the drug.
Take 1-2 tablets 3 times a day or 1-2 teaspoons of a solution 3 times a day. Depending on the severity of the condition, in the first 3 days the frequency of admission can be increased to 4-6 times a day.The duration of therapy depends on the severity of the disease and is determined by the attending physician.
Side effect
- reactions of increased individual sensitivity to the components of the drug are possible.
If these side effects are aggravated or the patient has noticed any other side effects not listed in the instructions, you should inform your doctor.
Contraindications
- increased individual sensitivity to the components of the drug;
- Children under 3 years of age, due to insufficient data on efficiency and safety.
Application in pregnancy and lactation
The safety of the use of Rengalin in pregnant women and during breastfeeding has not been studied. During pregnancy and during breastfeeding, the drug is used only if the intended benefit to the mother exceeds the potential risk to the fetus and the baby. The benefit / risk ratio is determined by the attending physician.
Use in children
The drug is contraindicated in children under the age of 3 years (due to insufficient data on efficacy and safety).
special instructions
With caution use a solution or syrup in patients with diabetes mellitus.
Patients with diabetes should remember that each teaspoon (5 ml) of the drug contains 0.3 g of maltitol, which corresponds to 0.02 XE. For the metabolism of maltitol, insulin is needed, although due to slow hydrolysis and absorption in the gastrointestinal tract, the need for insulin is small.
Impact on the ability to drive vehicles and manage mechanisms
Rengalin does not affect the ability to drive vehicles and other potentially dangerous mechanisms.
Drug Interactions
Lozenges. Cases of incompatibility with other drugs have not been registered to date.
Solution for oral administration. In the course of clinical trials, no data were obtained on the interaction of the Rengalin preparation with other drugs used as concomitant therapy.
Analogues of the drug Rengalin
Rengalin does not have structural analogs for the active substance. The drug based on homeopathic components has no analogues of the active substance.
Analogues on the curative effect (means for treating cough):
- Ambroxol;
- Antussin;
- Bromhexine;
- Bronchalamine;
- Bronchicum;
- Bronchicum inhalate;
- Bronchicum cough lozenges;
- Bronchicum cough syrup;
- Broncholitin;
- Bronhosan;
- Hexapneumine;
- Herbion syrup of primrose;
- Herbion syrup of plantain;
- Glycodine;
- Chest fee;
- Breathe;
- Insty;
- Carbocysteine;
- Kodelak;
- Codipron;
- Codterpine;
- Broncho's Witchcraft;
- Coldrex bronchus;
- Levopron;
- Libexin;
- Linkas;
- Linkas Lor;
- Lordestin;
- Mentoclar;
- Metovit;
- Mukaltin;
- Neo Codion;
- Neo Codion for children;
- Neo Cody for babies;
- Omnitus;
- Expectorant collection;
- Paxelidine;
- Panatas Forte;
- Pectosol;
- Pectusin;
- Pulmeks;
- Rinicold Bronho;
- Sedotussin;
- Sinecod;
- Solutan;
- Stoat;
- Stoptussin;
- Terpinkod;
- Travisil;
- Tussin;
- Tusuprex;
- Falimint;
- Fervex from a dry cough;
- Eucabal drops from cough;
- Eladon;
- Elisei;
- Erespal;
- Erispirus.
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