Mirror - instructions for use, analogs, reviews and release forms (alcohol solution or antibiotic lotion for external use) drugs for the treatment of acne or acne in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Mirror. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Zerkalina in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Zerkalina in the presence of existing structural analogues. Use for the treatment of acne or acne, acne in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Mirror - a drug based on Clindamycin - an antibiotic of the group of lincosamides active against all strains of Propionibacterium acnes. Inhibits the synthesis of proteins in the microbial cell due to interaction with the 50S-subunits of the ribosomes. After application to the skin, the amount of free fatty acids on the skin surface decreases from about 14% to 2%.

Composition

Clindamycin hydrochloride + excipients.

Pharmacokinetics

Clindamycin rapidly accumulates in comedones (acne), where it exhibits antibacterial activity. The average concentration of antibiotic in the content of comedones after application of the solution is significantly higher than the minimum inhibitory concentration for all strains of Propionibacterium acnes, the causative agent of acne. After applying clindamycin hydrochloride solution to the skin in blood and urine, very low concentrations of clindamycin are determined.

Indications

• treatment of acne vulgaris.

Forms of release

Solution for external use (sometimes mistakenly called lotion).

Other dosage forms, be it ointment, cream or gel, at the time of publication of the drug in the Directory did not exist.

Instructions for use and how to use them

Outwardly.The solution is applied to the affected area of ​​the previously cleaned and dried skin 2 times a day, in the morning and in the evening. The course of treatment: to obtain satisfactory results, treatment should be continued for 6-8 weeks, and if necessary, continue for up to 6 months.

Side effect

• irritation (at the application site);
• burning, itching, dry skin;
• erythema;
• peeling;
• increased sebum secretion;
• contact dermatitis;
• with resorption there is a possibility of developing pseudomembranous enterocolitis.

Contraindications

• Crohn's disease;
• ulcerative colitis (including in the anamnesis);
• pseudomembranous colitis (including in the anamnesis);
• increased sensitivity to clindamycin or lincomycin, as well as other components of the drug in the history.

Application in pregnancy and lactation

Perhaps the dermal application of Mirrorin solution during pregnancy, if the intended benefit for the mother exceeds the potential risk to the fetus.

If it is necessary to use during lactation, it is recommended to stop breastfeeding.

Use in children

Use with caution in children under 12 years of age.

special instructions

When using the drug should avoid contact with the eyes and the oral cavity, and after use it is necessary to wash your hands.

Use with caution in patients with allergies.

Accidental overdose is unlikely because of the local application of the drug.

Drug Interactions

It is not recommended that clindamycin chloride be used concomitantly with other acne treatment products containing exfoliating, softening and abrasive substances (eg benzoyl peroxide, tretinoin, resorcinol, salicylic acid, sulfur) because of the possible cumulative irritant effect on the skin.

Clindamycin and Erythromycin are antagonists, as a result of which simultaneous use of these antibiotics is not recommended.

There is cross-resistance between clindamycin and lincomycin.

May enhance the effect of muscle relaxants, disrupting neuromuscular transmission. Care must be taken in using.

Analogues of the drug Zerkalin

Structural analogs for the active substance:

• Dalacin;
• Klimitsin;
• Clindamycin;
• Klindatop;
• Clindefer;
• Clindacine;
• Klindachin Prolong;
• Klindes;
• Klindovit.

Analogues on the curative effect (remedies for the treatment of acne or acne):

• Aquazan;
• Acnekutan;
• Androkur;
• Arthromax;
• Basiron AC;
• Balian;
• Bassado;
• Bellune 35;
• Betaspan Depot;
• Betusil;
• Biseptol;
• Bonade;
• Wilprafen;
• Wilprafen solute;
• Delex Acne gel from acne;
• Deleks Acne cleansing lotion;
• Desquam;
• Jess;
• Jess Plus;
• Diane 35;
• Dimephosphone;
• Doxal;
• Doxycycline;
• Yeast beer;
• Genetta;
• Zinerit;
• Zitrolid forte;
• Clenzite;
• Curious;
• Kutis compositum;
• Lei;
• Purge of Puree;
• Metronidazole;
• Microfolline;
• Monoclin;
• Piolizin;
• Proderm;
• Retinoic ointment 0.05 and 0.1%;
• Roaccutane;
• Rosamet;
• Roxithromycin Lek;
• Silhouettes;
• Skinoren;
• Streptonitol;
• Sudokrem;
• Chloe;
• Zinctal;
• Cynovitis;
• Cytale;
• Eplan;
• Erica 35;
• Unidox Solutab;
• Yarina Plus.

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