Bronchorus - instructions for use, reviews, analogs and forms of release (30 mg tablets, syrup) for cough for bronchitis, pneumonia, asthma in adults, children (including infants and newborns) and pregnancy. Composition

In this article, you can read the instructions for using the drug Bronhores. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Bronchorus in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Bronhores in the presence of existing structural analogues.Use for the treatment of cough in bronchitis, pneumonia, asthma and bronchiectasis in adults, children (including infants and newborns), as well as during pregnancy and lactation. Composition of the preparation.

Bronhores - mucolytic and expectorant drug. Has a secreto-motor, secretolitic and expectorant action.

Ambroxol (the active substance of the drug Bronchorus) stimulates the motor activity of the cilia of the ciliated epithelium of the bronchial mucosa (mukinetic or secretory effect).

Peristaltic contractions in the spiral of ciliary cells of the bronchial epithelium excrete mucus from the bronchial tree (mucociliary transport or mucociliary clearance). Bronchorus significantly improves mucociliary transport.

Ambroxol stimulates serous cells of the glands of the bronchial mucosa, increases the content of the mucous component of sputum and normalizes the disturbed ratio of serous and mucous components of sputum. By activating hydrolysing enzymes and enhancing the release of lysosomes from Clara cells, reduces the viscosity of the sputum and its adhesive properties (mucolytic or secretolytic action).

Bronchorus increases the synthesis and secretion of surfactant (surfactant) in the alveoli and bronchi.

As a result of these mechanisms, the viscosity of the sputum is significantly reduced and its expectoration is improved.

When administered orally, the effect of the drug comes in 30 minutes and lasts for 6-12 hours.

Composition

Ambroxol hydrochloride + excipients.

Pharmacokinetics

Absorption is high, C max in the blood plasma is achieved 2 hours after ingestion. Binding to plasma proteins - 80%. Penetrates through the blood-brain barrier (GEB), the placental barrier, excreted in breast milk. Metabolized in the liver with the formation of dibromantranilic acid and glucuronic conjugates. It is excreted by the kidneys: 90% in the form of water-soluble metabolites, unchanged - 10%.

Indications

Acute and chronic diseases of the respiratory tract, accompanied by the formation of viscous sputum:

• acute and chronic bronchitis;
• pneumonia;
• bronchial asthma with difficulty in sputum discharge;
• bronchiectatic disease;
• COPD.

Forms of release

Tablets 30 mg.

Syrup for oral administration.

Instructions for use and dosing regimen

Pills

Inside, after eating, squeezed a lot of liquid.

Adults and children over 12 years - 1 tablet (30 mg) 3 times a day. If necessary, to enhance the therapeutic effect, you can appoint 2 tablets (60 mg) 2 times a day. In severe cases, the dose is not reduced throughout the course of treatment.

It is not recommended to take the drug for more than 5 days without consulting a doctor.

Syrup

Children under 12 years of age Bronchorus are prescribed in the form of syrup.

1 teaspoon (5 ml) of syrup contains 15 mg of Ambroxol hydrochloride.

Inside, during a meal or after a meal, with enough liquid (half a glass of water, tea or juice).

Adults and children over 12 years - the first 2-3 days of 10 ml syrup (2 teaspoons) 3 times a day, then - 10 ml syrup (2 teaspoons), 2 times a day, or to 5 ml syrup (1 teaspoon spoon) 3 times a day. In severe cases, the dose is not reduced throughout the course of treatment - 10 ml of syrup (2 teaspoons) 3 times a day.

Children aged 5-12 years are prescribed 5 ml of syrup (1 teaspoonful) 2-3 times a day; children aged 2-5 years - 2.5 ml syrup (1/2 teaspoon) 3 times a day; From birth to 2 years - 2.5 ml of syrup (1/2 teaspoon) 2 times a day.

It is not recommended to take the drug for more than 4-5 days without consulting a doctor.

Treatment of children under the age of 2 years should only be carried out under the supervision of a doctor.

During the use of the drug is a plentiful drink.

Side effect

• diarrhea, constipation;
• dry mouth;
• gastralgia;
• nausea, vomiting;
• dryness of the mucous membranes of the respiratory tract;
• rhinorrhea;
• skin rash;
• hives;
• angioedema;
• allergic dermatitis;
• anaphylactic shock;
• general weakness;
• headache;
• exanthema;
• dysuria.

Contraindications

• 1 trimester of pregnancy;
• children under 12 years (only for tablets). Children under 12 years of age are prescribed Bronchorus in the form of syrup;
• hypersensitivity to the components of the drug.

In case of lactose intolerance (in case of glucose / galactose absorption disorder or sucrose / isomaltase insufficiency), it should be taken into account that lactose is included in the formulation in the form of tablets.

Patients with hereditary intolerance to fructose should not take the drug in the form of a syrup (because the composition of the drug includes sorbitol).

Application in pregnancy and lactation

If it is necessary to use Bronchorus in the 2nd and 3rd trimesters of pregnancy, one should evaluate the potential benefit of therapy for the mother and the possible risk to the fetus.

During the period of breastfeeding, the drug should be used with caution, since ambroxol is excreted in breast milk.

Use in children

Contraindicated in children under 12 years of age (in the form of tablets).

Children under 12 years of age Bronchorus are prescribed in the form of syrup.

Inside, during a meal or after a meal, with enough liquid (half a glass of water, tea or juice).

1 teaspoon (5 ml) of syrup contains 15 mg of ambroxol hydrochloride.

Children aged 5-12 years are prescribed 5 ml of syrup (1 teaspoonful) 2-3 times a day; children aged 2-5 years - 2.5 ml syrup (1/2 teaspoon) 3 times a day; From birth to 2 years - 2.5 ml of syrup (1/2 teaspoon) 2 times a day.

It is not recommended to take the drug for more than 4-5 days without consulting a doctor.

Treatment of children under the age of 2 years should only be carried out under the supervision of a doctor.

special instructions

Do not combine with antitussive drugs that make it difficult to withdraw phlegm.

The drug in the form of syrup does not contain sugar. Patients with diabetes can be given a syrup: 5 ml of syrup contains sorbitol and saccharin in an amount corresponding to 0.18 XE.

The drug in the form of a syrup can cause a laxative effect,since the content of sorbitol in a daily dose can exceed 10 mg (600 mg of sorbitol is contained in 1 ml of syrup, and the daily dose can reach 30 ml, 18 g of sorbitol, respectively).

With caution apply for liver failure, kidney failure, peptic ulcer of the stomach and duodenum, in the 2nd and 3rd trimesters of pregnancy, during lactation (breastfeeding).

Impact on the ability to drive vehicles and manage mechanisms

During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Drug Interactions

Simultaneous use of the Bronchorus drug with antitussive drugs leads to difficulty in withdrawing sputum on the background of a reduction in cough.

Ambroxol increases the penetration into the bronchial secret of amoxicillin, cefuroxime, Erythromycin and doxycycline.

Analogues of the drug Bronhorus

Structural analogs for the active substance:

• Ambrogen;
• Ambro Hexal;
• Ambroxol;
• Ambrolan;
• Ambrolore;
• Ambrosan;
• Ambrosol;
• Bronoxoxol;
• Wicks Active AmbroMed;
• Dephlegmine;
• Bronchovern drops;
• Lazolvan;
• Lazognin;
• Medox;
• Mucobron;
• Neo Bronhol;
• Remebroks;
• Suprima-kof;
• Thoraxol Solidshn Tablets;
• Fervex from coughing;
• Flavamed;
• Flavamed forte;
• Haliksol.

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