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Influvac - instructions for use, reviews, analogs and release forms (suspension for intramuscular and subcutaneous administration) of the vaccine for the prevention of influenza in adults and children from 6 months (including infants and newborns). Composition and complications

Influvac - instructions for use, reviews, analogs and release forms (suspension for intramuscular and subcutaneous administration) of the vaccine for the prevention of influenza in adults and children from 6 months (including infants and newborns). Composition and complications

In this article, you can read the instructions for using the drug Influwak. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Influvac in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Influvac with available structural analogues.Use of the vaccine for the prevention of influenza in adults and children from 6 months (including infants and newborns), as well as during pregnancy and lactation. Composition and complications of the drug.

 

Influwak - is a trivalent inactivated influenza vaccine consisting of surface antigens (HA, HA) of influenza A and B viruses grown in chick embryos. The antigenic composition of influenza vaccine is updated annually according to WHO recommendations.

 

Forms specific immunity to influenza A and B influenza viruses, which usually occurs 14 days after vaccination and lasts up to 1 year.

 

Composition

 

One dose of vaccine (0.5 ml) contains haemagglutinin (HA) and neuraminidase (HA) of the following virus strains: A (H3N2) + A (H1N1) + B + excipients.

 

Indications

 

Prevention of influenza in adults and children from 6 months (including infants and newborns).

 

Vaccination is recommended for all individuals and, above all, for the following categories of the population at increased risk in case of a combination of influenza with already existing diseases / conditions:

  • persons older than 65 years, regardless of their health status;
  • patients with respiratory diseases;
  • patients with cardiovascular diseases of any etiology;
  • patients with chronic renal insufficiency;
  • patients with diabetes mellitus;
  • patients with immunodeficiency diseases (HIV infection, malignant blood diseases, etc.) and patients receiving immunosuppressants, cytotoxic drugs, radiation therapy or high doses of corticosteroids;
  • children and adolescents (from 6 months to 18 years of age) receiving long-term preparations containing acetylsalicylic acid, and therefore subject to an increased risk of developing Ray's syndrome due to influenza infection;
  • pregnant women (2-3 trimester). Pregnant women belonging to the categories at increased risk should be vaccinated regardless of the stage of pregnancy.

 

Forms of release

 

Suspension for intramuscular and subcutaneous injection (injections in ampoules for injection).

 

Instructions for use and usage diagram

 

Intramuscularly or subcutaneously (deep). It is strictly forbidden to administer the drug intravenously. Vaccination is carried out annually in the autumn period.Adults and adolescents (from age 14) - 0.5 ml once, for children: from 6 months to 3 years - 0.25 ml, from 3 to 14 years - 0.5 ml once; children who had not previously had the flu and not vaccinated, as well as patients with immunodeficiency - twice with an interval of 4 weeks.

 

Side effects and complications

  • thrombocytopenia;
  • allergic reactions;
  • anaphylactic shock;
  • headache;
  • paresthesia;
  • convulsions;
  • encephalomyelitis;
  • neuritis;
  • Guillain-Barre syndrome;
  • vasculitis with transient renal dysfunction;
  • fatigue and neuralgia, which do not require treatment and which take place after 1-2 days;
  • local reactions when the vaccine is introduced (redness, swelling, soreness, tightness, ecchymosis);
  • increased body temperature;
  • malaise;
  • shiver;
  • sweating;
  • soreness in the muscles and joints.

 

Contraindications

  • hypersensitivity to the chicken protein or to any other component of the vaccine;
  • severe temperature or allergic reactions after previous vaccination with subunit influenza vaccines.

 

Vaccination is postponed until the end of acute manifestations of the disease and exacerbation of chronic diseases. With mild ARVI, acute intestinal and other diseases, vaccination is carried out immediately after the temperature is normalized.

 

Application in pregnancy and lactation

 

Experience shows that Influvac does not have a teratogenic or toxic effect on the fetus. The Influvac vaccine can be used during lactation.

 

Use in children

 

Vaccination against influenza has been shown to children from 6 months of age.

 

special instructions

 

The vaccine retains its properties for 12 months. The expiration date is June 30 of the year following the year of issue. Do not use after the expiration date indicated on the package.

 

In the room where the vaccination is carried out, it is necessary to have medicines for the treatment of anaphylactic shock (adrenaline, glucocorticoids and other drugs).

 

The drug may contain an undetectable residual amount of gentamicin, therefore caution should be exercised when vaccinating individuals with hypersensitivity to aminoglycosides.

 

Guidelines for handling disposable syringes

 

Before administration, the vaccine should be warmed to room temperature. Immediately before the injection, the syringe must be shaken, the protective cap removed from the needle and the air removed from the syringe by holding it upright with the needle and slowly pressing the piston.When a dose of 0.25 ml is introduced, the movement of the syringe piston is stopped at a time when its inner surface reaches the lower edge of the needle retainer.

 

Drug Interactions

 

Influvac can be used concurrently with other vaccines (vaccines should be injected into different parts of the body with different syringes). There may be an increase in side effects.

 

If the patient receives immunosuppressive therapy, the immune response can be reduced.

 

After vaccination, it is possible to obtain false positive results of serological tests (with the enzyme immunoassay (ELISA)), which are caused by the production of IgM after vaccination.

 

Incompatibilities: incompatibilities are unknown.

 

Analogues of the drug Influvac

 

Vaccines for the prevention of influenza:

  • Agrippal S1;
  • The antigen of the influenza A virus is allantoic;
  • Antigen of the influenza virus type A allantoic (H1N1);
  • Antigen of the influenza virus type A allantoic (H3N2);
  • Antigen of the influenza virus type B;
  • Begrivac;
  • Grippol;
  • Vaxigrip;
  • Vaccine influenza allantoic intranasal live dry;
  • Vaccine influenza inactivated eluate-centrifuge liquid;
  • Vaccine influenza inactivated eluate-centrifuge liquid (Influenza vaccine);
  • Vaccine influenza chemical adsorbed killed liquid (AGH vaccine);
  • Grippovac;
  • Inflexal V;
  • Influvir;
  • Microflu;
  • Monovalent substance of influenza type B virus (split, inactivated);
  • Monovalent substance of influenza A virus (split, inactivated);
  • Orniflu;
  • Pandeflu;
  • Sovirnipp;
  • Ultraviolet;
  • Ultrashwac;
  • Ultrix;
  • Fluuarix;
  • Fluvaxin.

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