Revalgine - instructions for use, analogs, reviews and release forms (tablets, injections in injections) an anesthetic for the treatment of pain in neuralgia, sciatica, lumbago, colic in adults, children and pregnancy. Composition

In this article, you can read the instructions for the use of an anesthetic drug Revalgine. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Revalgine in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Revalgin with existing structural analogues.Use to treat pain in neuralgia, sciatica, lumbago, colic in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Revalgine - spasmoanalgesic. The composition of the drug includes non-narcotic analgesic metamizole sodium (analgin), myotropic antispasmodic drug pituophenone hydrochloride and anticholinergic agent fenpiverinia bromide.

Metamizole is a derivative of pyrazolone. It has analgesic, antipyretic and anti-inflammatory action.

Pitophenone, like papaverine, has a direct myotropic effect on the smooth muscles of the internal organs and causes it to relax.

Fenpierinium due to anticholinergic action has an additional relaxing effect on smooth muscle.

The combination of the three components of the drug leads to a mutual enhancement of their pharmacological action, expressed in relieving the pain, relaxing the smooth muscles, reducing the fever.

Composition

Metamizole + Pitophenone hydrochloride + Fentpuverinium bromide + excipients.

Indications

• mild to moderate pain syndrome with spasms of smooth muscles of internal organs - renal and biliarycolic, intestinal spasms, dysmenorrhea and other spastic conditions of internal organs;
• for short-term symptomatic treatment for headaches, migraine pain, joint pain, neuralgia, ischialgia, myalgia;
• as an adjuvant can be used to reduce pain after surgical and diagnostic interventions;
• to reduce the elevated body temperature for colds and infectious and inflammatory diseases.

Forms of release

Pills.

Solution for injections (injections in ampoules).

Other dosage forms, whether rectal suppositories, ointment or gel capsules, at the time of publication of the drug in the Directory did not exist.

Instructions for use and dosing regimen

Pills

Adults and adolescents over 15 years are prescribed inside (preferably after eating) 1-2 tablets 2-3 times a day. The daily dose should not exceed 6 tablets. Duration of reception no more than 5 days.

An increase in the daily dose of the drug or the duration of treatment is possible only under the supervision of a physician.

In children, the drug is used only as directed by a doctor. Dosage for children 6-8 years -1/2 tablets; for children 9-12 years old - 3/4 tablets; for children 13-15 years - 1 tablet; multiplicity of appointment - 2-3 times a day.

Other dosage regimens are possible only after consultation with a physician.

Ampoules

Parenterally (intravenously, intramuscularly).

Adults and adolescents over 15 years of age with acute severe colic are administered intravenously slowly (1 ml for 1 minute) 2 ml each; if necessary, again after 6-8 hours. For slow intravenous administration, usually 2 ml of the drug is sufficient.

Intramuscularly inject 2 ml of solution 2 times a day; daily should not exceed 4 ml. The duration of treatment is not more than 5 days.

In / m or in / in Revalgin is prescribed to children according to their age in the following single doses:

• 3-11 months (5-8 kg) - intravenously the drug is not administered - 0.1-0.2 ml dose for intramuscular injection;
• 1-2 years (9-15 kg) - 0.1-0.2 ml dose for intravenous administration - 0.2-0.3 ml dose for intramuscular injection;
• 3-4 years (16-23 kg) - 0.2-0.3 ml dose for intravenous administration - 0.3-0.4 ml dose for intramuscular injection;
• 5-7 years (24-30 kg) - 0.3-0.4 ml dose for intravenous administration - 0.4-0.5 ml dose for intramuscular injection;
• 8-12 years (31-45 kg) - 0.5-0.6 ml dose for intravenous administration - 0.6-0.7 ml dose for intramuscular injection;
• 12-15 years - 0.8-1.0 ml dose for intravenous administration - 0.8-1.0 ml dose for intramuscular injection.

If necessary, repeated administration of the drug in the same doses may be prescribed.

The solution is incompatible in one syringe with other drugs.

Before the injection of the injection solution, it should be warmed in the hand.

Side effect

• possible allergic reactions (skin rash, itching, very rarely - anaphylactic shock, urticaria);
• angioedema;
• burning sensation in the epigastric region;
• dry mouth;
• headache;
• dizziness;
• a decrease in blood pressure;
• tachycardia;
• cyanosis;
• disorders of hematopoiesis: thrombocytopenia, leukopenia, agranulocytosis (can manifest itself with the following symptoms: unmotivated rise in temperature, chills, sore throat, difficulty swallowing, stomatitis, and development of phenomena of vaginitis or proctitis);
• provoking an attack of bronchospasm;
• malignant exudative erythema (Stevens-Johnson syndrome);
• toxic epidermal necrolysis (Lyell's syndrome);
• impaired renal function;
• oliguria, anuria, proteinuria;
• interstitial nephritis;
• staining the urine in red;
• decreased sweating;
• paresis of accommodation;
• difficulty urinating;
• when administered intramuscularly, infiltrates are possible at the site of administration.

Contraindications

• oppression of bone marrow hematopoiesis;
• stable and unstable angina;
• chronic heart failure in the stage of decompensation;
• marked violations of the liver or kidneys;
• deficiency of glucose-6-phosphate dehydrogenase;
• tachyarrhythmia;
• acute intermittent porphyria;
• closed-angle form of glaucoma;
• hyperplasia of the prostate (with clinical manifestations);
• intestinal obstruction and megacolon;
• collapse;
• pregnancy (1 trimester and the last 6 weeks);
• lactation period;
• early childhood (up to 3 months or with a body weight of less than 5 kg);
• hypersensitivity to pyrazolone derivatives (butadione) and other components of the drug.

Application in pregnancy and lactation

The drug Revalgin is contraindicated in pregnancy (1 trimester and the last 6 weeks) and during lactation.

Use in children

For children and adolescents under 18, the drug should be used only as directed by the doctor

In early childhood (up to 3 months or with a body weight of less than 5 kg, that is, in infants) is contraindicated.

special instructions

Do not use to relieve acute pain in the abdomen (until finding out the cause).

During the treatment with the drug, alcohol should not be used.

Parenteral administration is usually used in emergency cases (renal or hepatic colic) and in those cases when ingestion is impossible (or absorption from the digestive tract is impaired).Special caution is required with the introduction of 2 ml of solution and more (risk of a sharp decrease in blood pressure). In / in the injection should be done slowly, in the supine position and under the control of blood pressure, heart rate and respiratory rate.

With prolonged (more than a week) application of the drug, control of the picture of peripheral blood and the functional state of the liver is necessary.

Impact on the ability to drive vehicles and manage mechanisms

During drug treatment it is not recommended to drive vehicles and engage in other potentially hazardous activities requiring quick physical and mental reaction.

Drug Interactions

The simultaneous use of revalgine with other non-narcotic analgesics may lead to a mutual enhancement of toxic effects.

Tricyclic antidepressants, oral contraceptives, Allopurinol disrupt metamizole metabolism in the liver and increase its toxicity.

Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the action of metamizole.

Simultaneous use with cyclosporine reduces the level of the latter in the blood.

Sedatives and tranquilizers increase the analgesic effect of metamizole sodium.

When co-administered with H1-histamin blockers, butyrophenones, phenothiazines, amantadine and quinidine, m-cholinolytic action may be enhanced.

When combined with ethanol (alcohol) - mutual enhancement of effects.

Simultaneous use with chlorpromazine or other phenothiazine derivatives can lead to the development of severe hyperthermia.

Radiopaque drugs and colloidal blood substitutes should not be used during treatment with drugs containing metamizole sodium.

Metamizole sodium, displacing from the bond with protein oral hypoglycemic drugs, indirect anticoagulants, glucocorticosteroids and indomethacin, may increase the severity of their action.

The effect is enhanced by codeine, H2-histamin blockers and Propranolol (slows the inactivation of metamizole sodium).

The solution for injection is pharmaceutically incompatible with other drugs.

If you need to use these and other medications at the same time, you should consult your doctor.

Analogues of Revalgin

Structural analogs for the active substance:

• Baralgetas;
• I took it;
• Bralangin;
• Geomag;
• Maxigan;
• Plenalgin;
• Renalgan;
• Spasgan;
• Spazmalgon;
• Spazmaline;
• Spazmil M;
• Spazmoblok;
• Spasmopharm;
• Trinalgin.

Analogues on the curative effect (means for treating sciatica):

• Anopyrine;
• Apizarthron;
• Bengay;
• Betalgon;
• Bralangin;
• Brufen;
• Brufen retard;
• Voltaren;
• Voltaren Emulgel;
• Dexalgin;
• Diazepec;
• Diklobene;
• Diqlovit;
• Dicloran;
• Diclofenac;
• Diprospan;
• Dolgit;
• Indomethacin;
• Indotard;
• Clynoril;
• Coffedon;
• Adhesive plaster medical Nanoplast forte;
• Maxigan;
• Matarin plus;
• Nyz;
• Naprios;
• Neurodiclavitis;
• Neuromultivitis;
• Nikofleks;
• Nimulid;
• Novigan;
• Oruvel;
• Panadol;
• Piroxicam;
• Pliwalgin;
• Radiculosan;
• Rapten Duo;
• Revmon gel;
• Sedalgin Neo;
• Sinusan;
• Solpadein;
• Spasgan;
• Spazmalgon;
• Surgham;
• Tenikam;
• Tilcotyl;
• Fastum gel;
• Finalgon;
• Flamadex;
• Flamax;
• Fleksen;
• Cefecon H;
• Espol;
• Efkamon;
• Yunispaz.

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