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Anauran - instructions for use, analogs, testimonials and release forms (ear drops) based on antibiotics for the treatment of external and otitis media in adults, children and pregnancy. Composition

Anauran - instructions for use, analogs, testimonials and release forms (ear drops) based on antibiotics for the treatment of external and otitis media in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Anauran. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of experts on the use of Anauran in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Anauran in the presence of existing structural analogs. Use for the treatment of external and otitis media before the perforation of the membrane in adults, children, as well as during pregnancy and lactation.Composition of a combined preparation based on antibiotics.

 

Anauran - a combined preparation for topical application, has an antibacterial and local anesthetic effect.

 

Neomycin sulfate is an aminoglycoside antibiotic of broad spectrum. Bactericidal against Gram-positive (Staphylococcus spp. (Staphylococcus aureus), Streptococcus pneumoniae (strep)) and Gram-negative (Escherichia coli (E. coli), Shigella dysenteria (Shigella), Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp. (Proteus) ) of microorganisms; in respect of Streptococcus spp. - Low active.

 

Polymyxin B is a polypeptide antibiotic. It is active against gram-negative microorganisms: Escherichia coli, Shigella dysenteria, Shigella flexneri, Shigella boydii, Shigella sonnei, Salmonella typhi (salmonella), Salmonella paratyphi, Pseudomonas aeruginosa. It is active against Proteus spp., Mycobacterium spp. (mycobacterium), Gram-positive cocci, fungi. Has a weak local irritant effect.

 

Lidocaine - a local anesthetic, quickly eliminates pain and itching.

 

Composition

 

Polymyxin B sulfate + Neomycin sulfate + Lidocaine hydrochloride + excipients.

 

Pharmacokinetics

 

Pharmacokinetic studies were not carried out, because The drug is intended for topical administration and systemic effects are unlikely.

 

Indications

  • acute and chronic otitis externa;
  • average acute otitis media at the stage before perforation;
  • chronic exudative otitis media;
  • postoperative purulent complications after radical mastoidectomy, tympanoplasty, anthotomy, fenestration.

 

Forms of release

 

Ear drops.

 

Instructions for use and how to use them

 

Locally, into the external ear canal (in the ear) using a special pipette. After digging for a few minutes, keep your head tilted.

 

Adults - 4-5 drops 2-4 times a day, children - 2-3 drops 3-4 times a day, depending on the severity of the disease.

 

The course of treatment should not exceed 7 days.

 

Side effect

  • hyperemia, itching and flaking of the skin of the external auditory canal, which disappear without treatment after drug withdrawal.

 

Contraindications

  • hypersensitivity to any of the components of the drug.

 

Application in pregnancy and lactation

 

During pregnancy and lactation, the drug Anauran should be used only in case of emergency and under the supervision of a doctor.

 

Use in children

 

Children - 2-3 drops 3-4 times a day, depending on the severity of the disease.

 

In children under 1 year, the drug should be used only in case of emergency and under the supervision of a doctor.

 

special instructions

 

Anauran is used exclusively for ear disorders. In severe and persistent infections, local treatment should be supplemented with systemic use of antibiotics.

 

Long-term use of Anauran, as well as other antibiotics, can lead to the development of superinfection with drug-resistant microorganisms.

 

Systemic effects are unlikely due to low doses of the drug used. However, long-term treatment may cause systemic side effects, in particular, ototoxicity and nephrotoxicity due to absorption of neomycin.

 

Shelf life of the drug is 3 years. After opening the vial, use within 3 months.

 

Drug Interactions

 

Incompatible with monomycin, streptomycin, gentamycin, amikacin, netilmicin (possible to increase the ototoxic effect of the above antibiotics).

 

Analogues of the medicine Anauran

 

Anuran has no structural analogs for the active substance. The drug contains a unique combination of active ingredients in its composition.

 

Analogues on the pharmacological group (agents for the treatment of purulent otitis media):

  • Amoxicillin;
  • Ampicillin;
  • Augmentin;
  • Biseptol;
  • Witsef;
  • Dexon;
  • Diclomelan;
  • Doxilan;
  • Doxycycline;
  • Iodinol;
  • Candibiotics;
  • Clarithromycin;
  • Clindamycin;
  • Ximelin;
  • Levomycetin;
  • Lidaprim;
  • Microfleks;
  • Nazivin;
  • Oxamp;
  • Ospamox;
  • Ospen;
  • Otinum;
  • Otypax;
  • Otofa;
  • Otrivin;
  • Ofloxacin;
  • Ofloxin;
  • Oflotsid;
  • Panklav;
  • Recipro;
  • Ribomunyl;
  • Selemycin;
  • Sephril;
  • Siflox;
  • Soleksin;
  • Stadacillin;
  • Sultasin;
  • Sulfadimethoxin;
  • Sumamed forte;
  • Supraks;
  • Taromentine;
  • Tertsef;
  • Trimezol;
  • Uniflox;
  • Fazin;
  • Fromromide;
  • Furacilin;
  • Hemomycin;
  • Cefabol;
  • Cefazolin;
  • Cephalexin;
  • Cefotaxime;
  • Ceftazidime;
  • Ceftriaxone;
  • Ciprofloxacin;
  • Erythromycin phosphate;
  • Hermitage;
  • Yunidox Solutab.

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