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Grippol - instructions for use, reviews, analogs and forms of release (suspension or solution in syringes or ampoules for injection Plus, Neo) vaccines for vaccination and prevention of influenza in adults, children and pregnancy. Composition and set of strains

Grippol - instructions for use, reviews, analogs and forms of release (suspension or solution in syringes or ampoules for injection Plus, Neo) vaccines for vaccination and prevention of influenza in adults, children and pregnancy. Composition and set of strains

In this article, you can read the instructions for using the drug Grippol. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of specialists in the use of Grippol in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Grippol in the presence of existing structural analogues.Use for vaccination and prevention of influenza in adults, children, as well as during pregnancy and lactation. Composition and collection of influenza vaccine strains.

 

Grippol - a vaccine for the prevention of influenza. The vaccine forms a high specific immunity against influenza and is well tolerated by children and adults. After vaccination, antibodies appear after 8-12 days, immunity persists up to 12 months, incl. in the elderly. Protective titers of antibodies to influenza viruses after vaccination of persons of different ages are determined in 75-92% of vaccinated.

 

Inclusion in the preparation of immunomodulator Polyoxidonium provides an increase in immunogenicity and stability of antigens, allows to increase immunological memory, significantly reduce the vaccine dose of antigens, increase the resistance of the organism to other infections due to correction of the immune status.

 

Composition

 

Haemagglutinin of influenza A virus (strain H1N1) + Haemagglutinin of influenza type A (strain H3N2) + Hemagglutinin of influenza type B + Polyoxidonium + excipients.

 

Indications

 

Active preventive immunization against influenza in children from 6 months of age, adolescents and adults without age restriction:

  • persons over 60 years of age;
  • persons suffering from chronic somatic diseases (including diseases and malformations of the central nervous system, cardiovascular system and bronchopulmonary system, bronchial asthma, chronic kidney disease, diabetes mellitus, metabolic diseases, autoimmune diseases, allergic diseases (except allergy to chicken proteins), chronic anemia, congenital or acquired immunodeficiency, HIV-infected);
  • often ill ARI;
  • children of preschool age;
  • pupils;
  • medical workers;
  • employees of the service sector, transport, educational institutions, servicemen.

 

Forms of release

 

Suspension for intramuscular and subcutaneous administration (ampoules for injection) (Grippol and Grippol Neo).

 

Solution for intramuscular and subcutaneous injection.

 

Suspension for intramuscular and subcutaneous injection (syringes or ampoules for injection) (Grippol Plus).

 

Instructions for use, timing and technique of vaccine formulation

 

Vaccination is carried out annually in the autumn-winter period. It is possible to vaccinate at the beginning of an epidemic rise in the incidence of influenza.

 

Children aged 6 months to 3 years are vaccinated at a dose of 0.25 ml twice with an interval between injections of 4 weeks; or in a dose of 0.5 ml once, if the child in the previous season was vaccinated against the flu.

 

Children older than 3 years and adults without age limit of 0.5 ml once.

 

Patients with immunodeficiency can enter the vaccine twice in 0.5 ml with an interval between injections of 4 weeks.

 

The vaccine is injected intramuscularly or deeply subcutaneously into the upper third of the outer surface of the shoulder (in the deltoid muscle), to young children in the anterior anterior surface of the thigh.

 

Regulations for the introduction of the vaccine

 

Before use, the vaccine should be allowed to reach room temperature and shaken well. Remove the protective cap from the needle and remove air from the syringe by holding it upright with a needle up and slowly pressing the piston.

 

In order to immunize children who are injected with 0.25 ml (1/2 dose) of the vaccine, it is necessary to remove half the contents of the syringe by pressing the piston to a special risk marked on the syringe body or to the red label placed on the label edge and enter the remaining 0.25 ml.

 

Opening of ampoules and vials and the vaccination procedure are carried out with strict adherence to the rules of aseptic and antiseptic: before opening, the ampoule knife, ampoule neck or bottle stopper should be wiped with cotton wool soaked with 70% ethyl alcohol, open the ampoule or pierce the rubber stopper of the vial with a needle, and inject the vaccine into a disposable syringe and remove excess air from the syringe. Alcohol rubs the skin at the injection site. The drug in the opened ampoule or vial is not subject to storage.

 

Side effect

  • local reactions in the form of pain, hyperemia, compaction and edema at the site of administration;
  • malaise;
  • weakness;
  • low-grade fever;
  • general reactions in the form of a slight runny nose, sore throat, headache and fever above subfebrile;
  • allergic reactions, incl. immediate type;
  • neuralgia;
  • paresthesia;
  • neurological disorders;
  • myalgia.

 

The patient should be informed of the need to inform the physician of any adverse reactions expressed or not indicated in this manual.

 

Contraindications

  • allergic reactions to chicken protein and vaccine components;
  • allergic reactions to previously administered influenza vaccines;
  • acute feverish conditions or exacerbation of a chronic disease (vaccination is performed after recovery or during remission);
  • non-severe acute respiratory viral infections, acute intestinal diseases (vaccination is carried out after normalizing the temperature).

 

Application in pregnancy and lactation

 

Preclinical studies have shown that the vaccine Grippol influenza inactivated polymer-subunit does not have embryotoxic and teratogenic effects. The doctor takes the decision about vaccination of pregnant women individually taking into account the risk of infection with influenza and possible complications of influenza infection. Vaccination is most safe in the 2nd and 3rd trimesters of pregnancy.

 

Breastfeeding is not a contraindication for vaccination.

 

Use in children

 

Children aged 6 months to 3 years are vaccinated at a dose of 0.25 ml twice with an interval between injections of 4 weeks; or in a dose of 0.5 ml once, if the child in the previous season was vaccinated against the flu.

 

Children older than 3 years and adults without age limit of 0.5 ml once.

 

special instructions

 

The drug can not be administered intravenously.

 

In the offices where the vaccination is carried out, it is necessary to have medicines for anti-shock measures and relief of anaphylactic reaction.The vaccinated should be under medical supervision within 30 minutes after the introduction of the vaccine.

 

On the day of administration of the drug, the vaccinated should be examined by a physician with mandatory thermometry. At a temperature above 37.0 degrees Celsius, there is no vaccination.

 

It should be borne in mind that the preparation is not suitable for use in ampoules with broken integrity or marking, with changing physical properties (color, transparency), expired shelf life, violation of requirements for storage conditions.

 

Storage and transport

 

The drug should be stored out of reach of children, protected from light at a temperature of 2 to 8 degrees Celsius; Do not freeze. The drug, which has been frozen, is not subject to application. Shelf life - 1 year. The drug with expired shelf life is not subject to application.

 

Transportation of all types of covered transport in lightproof containers at a temperature of 2 to 8 degrees Celsius, in conditions that exclude freezing. Transportation is allowed at temperatures up to 25 degrees Celsius for 6 hours.

 

Influence on the ability to drive a car or control cars and mechanisms

 

Grippol does not affect the ability to drive a car or control cars and machinery.

 

Drug Interactions

 

The vaccine can be administered against the background of basic therapy of the underlying disease.

 

Vaccination of patients receiving immunosuppressive therapy may be less effective.

 

Grippol vaccine may be applied simultaneously inactivated and living vaccines National calendar prophylactic immunization (except BCG and BCG-M) and inactivated vaccines Immunization Schedule for epidemic indications (except rabies). Thus it is necessary to consider the contraindications to each of the applied vaccine formulations to be administered at different sites different syringes.

 

Analogues of the drug Grippol

 

Structural analogs for the active substance:

  • Grippol Neo;
  • Grippol plus;
  • MonoGripol;
  • MonoGriple Neo;
  • MonoGriple plus.

 

Analogues on the curative effect (funds for the treatment and prevention of influenza):

  • Algiers;
  • Alfaron;
  • Amizon;
  • Amiksin;
  • Anaferon;
  • Anaferon child;
  • Arbidol;
  • Biolin Cold;
  • Bronchicum;
  • Vaxigrip;
  • Vaccine influenza inactivated eluate-centrifuge liquid;
  • Viferon;
  • Hexapneumine;
  • Genferon Light;
  • Homeopathy;
  • Influenza from the cold and flu;
  • Grippferon;
  • Isoprinosine;
  • Immunal;
  • Immunoglobulin;
  • Immunorm;
  • Ingavirin;
  • Inflexal;
  • Influbene;
  • Influenza;
  • Influcid;
  • IRS 19;
  • Kagocel;
  • Carinate;
  • Karinat Forte;
  • Codipron;
  • Broncho's Witchcraft;
  • Coldrex;
  • Lavomax;
  • Libexin;
  • Linkas;
  • Mulcinex;
  • Neovir;
  • Orvire;
  • Oscillococcinum;
  • Padeviks;
  • Panavir;
  • Polyoxidonium;
  • Prophylactin C;
  • Reaferon EU Lipint;
  • Relenza;
  • Remantadine;
  • Rengalin;
  • Sakhol;
  • Sulfadimethoxin;
  • Tamiflu;
  • Fluuarix;
  • Cycloferon;
  • Cigapan;
  • Eifitol;
  • Eladon;
  • Endobulin;
  • Ergoferon.

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Reviews (1):
Guests
Olga
Previously, I was very skeptical about vaccination against influenza, I simply did not believe in their effectiveness, or maybe the negative opinion on the network affected me. And so every year not only children, but I myself had the flu. Children at times were so hard to bear that at one point I decided to raise the issue of vaccination against the flu and we vaccinated the whole family with the vaccine of our domestic producer Grippol Plus.And what do you think, we have never got sick in the whole winter! I was in shock. The vaccine does work. And the ratio of price and quality is excellent. Now only Grippol plus kolem and no other vaccines just do not trust. This vaccine has been tested by us for several years.

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