Tiloron - instructions for use, analogs, reviews and release forms (tablets and capsules 50 mg and 125 mg) of an antiviral drug for the treatment and prevention of influenza, hepatitis, herpes in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Tyloron. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Tyloron in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Tyloron in the presence of existing structural analogues.Use for the treatment and prevention of influenza, hepatitis, herpes in adults, children, as well as during pregnancy and lactation. Composition of antiviral drug.

Tyloron - low-molecular inducer of endogenous interferon. It is a synthetic compound of the aromatic series, belongs to the class of fluorenones. It stimulates the formation of interferons in the body of alpha, beta, gamma. The main structures that produce Interferon in response to tyloron administration are intestinal epithelial cells, hepatocytes, T-lymphocytes, granulocytes. After oral administration, the maximum production of interferon is determined in the intestine-liver-blood sequence after 4-24 hours. In human leukocytes, tyloron induces the formation of interferon, whose level in the blood is 250 U / ml.

It has an immunomodulatory effect: it stimulates bone marrow stem cells, depending on the dose, enhances antibody formation, increases the ratio of high-aspect / low-antibodies, reduces the degree of immunosuppression, restores the ratio of T-helpers / T-suppressors.

Composition

Tyloron + auxiliary substances.

Pharmacokinetics

After oral administration, it is rapidly absorbed from the digestive tract. Bioavailability is 60%.Binding to plasma proteins is about 80%. Not subject to biotransformation. It is excreted unchanged with faeces (70%) and urine (9%). Do not cumulate.

Indications

As part of complex therapy:

• viral hepatitis A, B and C;
• infections caused by viruses Herpes simplex type 1 and 2, Varicella zoster, cytomegalovirus;
• infectious-allergic and viral encephalomyelitis (multiple sclerosis, leukoencephalitis, uveoencephalitis);
• urogenital and respiratory chlamydia;
• non-gonococcal urethritis;
• pulmonary tuberculosis.

Treatment and prevention of influenza and other acute respiratory viral infections.

Forms of release

Tablets coated with 60 mg and 125 mg.

Capsules 125 mg.

Instructions for use and dosing regimen

Inside, after eating. Dose, frequency of admission and duration of treatment are set individually, depending on the indications; average single doses for adults - 125 - 250 mg, for children over 7 years - 60 mg.

In the treatment of influenza and other SARS: adults - in the first two days of the disease, 125 mg, then 125 mg after 48 hours. The course dose is 750 mg. For the prevention of influenza and other SARS: 125 mg once a week for 6 weeks.

Children older than 7 years with uncomplicated forms of influenza or other SARS - 60 mg once a day on days 1, 2 and 4 from the start of treatment (for the treatment of 180 mg - 3 tablets).If complications of influenza or other acute respiratory viral diseases occur, the drug is taken on days 1, 2, 4 and 6 from the start of treatment (240 mg for 4 tablets).

Side effect

• short-term chill;
• allergic reactions;
• dyspeptic symptoms.

Contraindications

• pregnancy;
• lactation (breastfeeding);
• children's age till 7 years;
• hypersensitivity to tilorone.

Application in pregnancy and lactation

Tiloron is contraindicated in pregnancy and lactation (breastfeeding).

Use in children

Contraindicated in children under 7 years.

special instructions

It is not recommended to apply Tyloron in doses exceeding the recommended ones, in order to avoid possible short-term depletion of immunocompetent cells.

In the complex therapy of neuroviral infections, tilorone is used under the supervision of a doctor.

Drug Interactions

Tiloron is compatible with antibiotics, traditional treatment of viral and bacterial diseases.

Analogues of the drug Tyloron

Structural analogs for the active substance:

• Aktaviron;
• Amiksin;
• Lavomax;
• Thilaxin;
• Tiloram;
• Tylorone dihydrochloride.

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