Timalin - instructions for use, reviews, analogs and forms of release (injections in ampoules) for the treatment of immunodeficiency, purulent and viral diseases in adults, children and pregnancy. Composition
In this article, you can read the instructions for using the drug Timalin. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Timalin in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Timalin in the presence of existing structural analogues. Use for the treatment of immunodeficiency, purulent and viral diseases in adults, children, as well as during pregnancy and lactation. Composition of the preparation.
Timalin - immunostimulating agent. It restores immunological reactivity (the reaction of the body to pathogenic stimuli, usually accompanied by the formation of protective properties of the body) - regulates the number and ratio of T- and B-lymphocytes (the blood constituents responsible for the formation of cellular and tissue protective forces of the organism) and their subpopulations, stimulates the reaction of cellular immunity (cellular protective forces of the body), enhances phagocytosis (the process of active capture and destruction by phagocytes (blood cells) of pathogenic microorganisms ganizmov), stimulates the processes of regeneration (regeneration) and hematopoiesis in case of their inhibition, and also improves the processes of cellular metabolism (metabolism).
A preparation of a polypeptide nature, obtained by extraction (extraction) from the thymus gland (thymus) of cattle.
Composition
Preparation of thymus of cattle + auxiliary substances.
Indications
- immunodeficiency states in adult patients with a predominant defeat of the T-system of immunity against the background of infectious, purulent and septic processes, lymphoproliferative diseases (lymphogranulomatosis, lymphatic leukemia);
- acute and chronic viral and bacterial infections;
- conditions associated with hypothyroidism (weakening of activity) of the thymus gland, with inhibition of immunity and hematopoiesis after radiation therapy or chemotherapy in cancer patients and in other conditions;
- with the purpose of preventing infectious and other complications, in the post-traumatic and postoperative periods, when administering large doses of antibiotics.
Forms of release
Lyophilizate for the preparation of solution for intramuscular injection (injections in ampoules for injection).
Other dosage forms, be it tablets or capsules, do not exist.
Instructions for use and dosing regimen
The drug is administered subcutaneously once a day (at night) at a dose of 40 μg / m2 body surface for 5-7 days. If necessary, treatment can be repeated.
With persistent impairment of immunity, the drug is administered in the same doses for 5-6 days, then 1 time every 7-10 days.
For treatment of surgical patients the drug is administered within 2 days before the operation and within 3 days after it.
With lymphoproliferative diseases, the drug is administered before and, if necessary, in the intervals between courses of antitumor therapy.
For treatment of recurrent ophthalmoherpes, the dose is 10 μg / m2 per day, with an interval of 1 day, for 14 days. The course of treatment is repeated after 4-6 months.
For the prevention of persistently recurring ophthalmoherpes in the period usually preceding the time of onset of relapse, every 3-6 months at 25-50 μg; course of treatment - 5 injections every other day.
The contents of the vial before injection are dissolved in 1-2 ml of isotonic sodium chloride solution. The drug is administered intramuscularly daily in the following doses: adults - 5-20 mg (30-100 mg per course of treatment), children under 1 year - 1 mg, 1-3 years - 1-2 mg, 4-6 years - 3 mg, 7-14 years - 3-5 mg for 3-10 days, depending on the severity of immunity disorders. If necessary, repeat the course of treatment (after 1-6 months).
With the preventive purpose, the drug is administered intramuscularly daily to adults of 5-10 mg, children - 1-5 mg for 3-5 days.
Side effect
- provocation of hyperimmune cytolysis;
- exacerbation of purulent infections;
- allergic reactions.
Contraindications
- hypersensitivity;
- atopic bronchial asthma;
- pregnancy.
Application in pregnancy and lactation
Timalin is contraindicated in pregnancy.
Use in children
Possible use in children according to the dosing regimen.
special instructions
Before using Timalin, the patient is recommended to undergo training in order to increase the release of T cell progenitors from the bone marrow. To this end, prescribed stimulant drugs: sodium nucleate, Pentoxyl, Methyluracil, Leukogen. They should be taken 10-14 days.
Drug Interactions
Not noted.
Analogues of Timalin
Structural analogs for the active substance:
- Vilozen;
- Tactivin;
- Timaktid;
- Timarin.
Analogues for the pharmacological group (immunostimulants):
- Actinolysate;
- Arpetolide;
- Affinoleukin;
- Beast;
- Betaleukin;
- Bioaron C;
- Bronho Vaxom;
- Vilozen;
- Viruter;
- Vitanam;
- Wobenzym;
- Gepon;
- Glutoxim;
- Deoxynate;
- Immunal;
- Immunomax;
- Immunorm;
- Imudon;
- Imunofan;
- Kipferon;
- Leukogen;
- Lycopid;
- Methyluracil;
- Myelopid;
- Moliksan;
- Sodium nucleate;
- Neovir;
- Pentoxyl;
- Pyrogenal;
- Polydane;
- Polymuramyl;
- Rexod;
- Ribomunyl;
- Ridostin;
- Ruzam;
- Stisamet;
- Stimforte;
- Tamerite;
- Tubosan;
- Uro Vaxom;
- Phlogenzyme;
- Cycloferon;
- Cytovir 3;
- Erbisol;
- Ergoferon;
- Estifan;
- Echinacea;
- Echinocor.
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