Candide - instructions for use, reviews, analogs and formulations (tablets or candles 500 mg vaginal, 1% cream, 2% gel, 1% solution) for the treatment of candidiasis (thrush) and mycoses in adults, children and pregnancy

In this article, you can read the instructions for using the drug Candide. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Candida in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Candida in the presence of existing structural analogues. Use to treat candidiasis (thrush) and other types of fungal infections in adults, children, as well as during pregnancy and lactation.

Candide - a broad-spectrum antifungal agent for external use, an imidazole derivative. Antimycotic effect associated with a violation of the synthesis of ergosterol, which is part of the cell membrane of fungi, which causes a change in its structure and properties and leads to lysis of the cell.

To Clotrimazole (active ingredient Candide) sensitive dermatophytes, yeast-like fungi (the genus Candida, Torulopsis glabrata, Rhodotorula), mold fungi, as well as the causative agent of the varicoloured Pityriasis versicolor and the causative agent of erythrasma.

Has antimicrobial effect against gram-positive (staphylococcus and streptococcus) and Gram-negative bacteria (Bacteroides, Gardnerella vaginalis), and also against Trichomonas vaginalis.

Pharmacokinetics

Clotrimazole is poorly absorbed through the skin and mucous membranes and has virtually no systemic effect.

With external application, the concentration of clotrimazole in the epidermis is higher than in the dermis and subcutaneous tissue.

Indications

• dermatophytosis of the head (including face), body, legs;
• mycosis of the nails;
• colored lichen;
• candidiasis of the skin;
• candidal paronychia;
• candidiasis vulvitis;
• Candidiasis balanitis;
• candidiasis of external genitalia and anorectal area;
• fungal diaper dermatitis;
• erythrasma.

Forms of release

Tablets or candles vaginal 500 mg.

Solution for local and external use 1%.

Gel for vaginal application 2%.

Cream for external use 1%.

Powder for external use 10 mg.

Candide B6 - vaginal tablets 100 mg (analogues of suppositories).

Candide B - cream for external use.

Instructions for use and dosing regimen

Vaginal or candle tablets

Introduced intravaginally, deeply, in the "lying on the back" position with slightly bent legs. 500 mg once (in the evening). A second course of treatment is possible after consulting a doctor.

For the sanation of the birth canal is recommended a single administration of 1 table.

Powder

Outwardly. Powder is applied to the affected skin 3-4 times a day. Improvement of the condition occurs within 3-5 days. For successful treatment, regular use of the drug is important. The duration of therapy is individual and depends on the severity and localization of the disease. To achieve full recovery, the drug should not be discontinued immediately after the acute symptoms of inflammation or subjective complaints have disappeared.

The duration of therapy should be, on average, about 4 weeks; with pityriasis deprivation 1-3 weeks, with erythrasma 2-4 weeks.With interdigital fungal foot erosions, it is recommended to continue therapy for about 2 weeks after relief of the symptoms of the disease.

Cream or gel

The necessary amount of cream or lotion is applied to the previously washed and dry affected area of ​​the skin 2-3 times a day. Treatment should continue for 2-4 weeks after the disappearance of clinical symptoms to ensure mycological cure and prevent relapse.

The drug in the form of lotion is used for large lesions and on the hairy areas of the skin.

Side effect

• burning;
• tingling at the site of application;
• erythema;
• the appearance of blisters;
• edema;
• irritation;
• peeling;
• itching;
• hives.

Contraindications

• 1 trimester of pregnancy;
• increased sensitivity to clotrimazole or excipients.

Application in pregnancy and lactation

It is not recommended to use the drug in the first trimester of pregnancy. The question of the expediency of prescribing the drug in the 2nd and 3rd trimesters should be decided individually after consultation of the doctor.

In clinical and experimental studies, a negative effect on the health of a woman or fetus is not established.

special instructions

To prevent urogenital reinfection, simultaneous treatment of sexual partners is necessary.

In case of trichomoniasis, other drugs with systemic action (eg Metronidazole inside) should be used in conjunction with Candida for a more successful treatment.

With a simultaneous infection of the labia and adjacent areas (candidiasis vulvitis), you should additionally undergo local treatment with Candida cream.

During pregnancy, vaginal pills should be treated without an applicator.

Patients with hepatic insufficiency should periodically monitor the functional state of the liver.

When signs of hypersensitivity or irritation appear, the treatment is stopped.

If there is no effect within 4 weeks, you should confirm the diagnosis.

Drug Interactions

Candide reduces the activity of amphotericin B and other polyene antibiotics.

When used simultaneously with natamycin and nystatin, the activity of clotrimazole may decrease.

Analogues of Candida

Structural analogs for the active substance:

• Amicon;
• Antifungole;
• Guine-Lotrimin;
• Imidil;
• Yenamazol 100;
• Kandibene;
• Candide-B6;
• Candisol;
• Kanesten;
• Canison;
• Clotrimazole;
• Clotrimazole-Acry;
• Lotrimin;
• Faktodin.

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