Ingaron - instructions for use, reviews, analogs and formulations (powder for the preparation of a solution in the nose, drops or spray, injections in ampoules for injection) of a drug for the treatment of hepatitis, herpes, leprosy in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Ingaron. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Inharone in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Ingaron in the presence of existing structural analogues.Use to treat hepatitis, tuberculosis, psoriasis, leprosy in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Ingaron - is a glycoprotein with a molecular weight of 20-25 kD and is known as an immune interferon. Obtained from stimulated human T-lymphocytes. At present, a technique for recombinant DNA using bacterial cells is increasingly being used to obtain Interferon gamma. Two types of interferon gamma gamma 1a and gamma 2a are known, differing in the sequence of amino acids in their chain at the 1 and 139 positions. Has a pronounced immunomodulating activity, as it enhances the expression of large histocompatibility complex 1 and 2 antigens; activates macrophages, enhances the activity of natural killers; reduces the expression of a subpopulation of B cells, monocytes and eosinophils induced by IL-4; and also reduces IgE production; stimulates the growth and differentiation of B cells.

Composition

Interferon gamma + excipients.

Indications

• treatment of chronic viral hepatitis C, chronic viral hepatitis B, HIV / AIDS infection and pulmonary tuberculosis in complex therapy;
• prevention of infectious complications in patients with chronic granulomatous disease;
• Treatment of oncological diseases in complex therapy as an immunomodulator, incl. in combination with chemotherapy;
• treatment of genital herpesvirus infection and herpes zoster (Herpes zoster) in monotherapy;
• treatment of urogenital chlamydiosis in complex therapy;
• treatment of chronic prostatitis in complex therapy;
• treatment of anogenital warts (human papilloma virus) and prevention of recurrence of the disease;
• psoriasis;
• as maintenance therapy for cutaneous and visceral leishmaniasis;
• Mycobacterial infection in HIV-negative patients with ineffective conservative therapy;
• leprosy;
• prevention of influenza and ARVI;
• as an alternative therapy for rheumatoid arthritis;
• eczema and atopic dermatitis, especially at high levels of IgE;
• as an additional agent for antibiotic therapy of lymphogranulomatosis.

Forms of release

Lyophilizate or powder for the preparation of a solution for intranasal administration of 100,000 IU (sometimes mistakenly referred to as nose drops or spray).

Lyophilizate or powder for the preparation of a solution for intramuscular and subcutaneous administration of 100,000 IU, 500,000 IU, 1,000,000 IU and 2,000,000 IU (injections in injectable vials).

Instructions for use and reception scheme

Nasal solution

Intranasally. The contents of the vial are dissolved in 5 ml of water for injection.

2 drops in each nasal passage after the toilet of the nasal passages 5 times a day for 5 - 7 days.

For the prevention of acute respiratory viral infection and influenza, when in contact with a patient and / or during supercooling, 2-3 drops in each nasal passage every other day for 10 days. If necessary, preventive courses are repeated. When a single contact is enough, one instillation.

After instillation it is recommended to massage the wings of the nose with your fingers for several minutes to distribute the drug evenly in the nasal cavity.

Ampoules for injections

The drug is administered intramuscularly or subcutaneously. The contents of the vial are dissolved in 2 ml of water for injection. The dose of the drug is set individually.

For treatment of patients with chronic viral hepatitis B, chronic viral hepatitis C, as well as HIV / AIDS infection and pulmonary tuberculosis, the average daily dose for adults is 500 00 ME.The drug is administered 1 time per day, daily or every other day. The course of treatment is from 1 to 3 months, if necessary, after 1-2 months, the course of treatment is repeated.

For the prevention of infectious complications in patients with chronic granulomatous disease, the average daily dose for adults is usually 500 000 ME. The drug is administered 1 time per day, daily or every other day. The course of treatment - 5-15 injections, if necessary, the course is prolonged or repeated after 10-14 days.

For the treatment of cancer, the average daily intake for adults is 500,000 ME. The drug is administered 1 time per day, every other day.

For the treatment of genital herpesvirus infection, herpes zoster (Herpes zoster) and urogenital chlamydia, the average daily dose for adults is 500,000 IU. The drug is administered 1 time per day, sc, every other day. The course of treatment is 5 injections.

For the treatment of chronic prostatitis, the daily dose is 100 000 ME. The drug is administered 1 time per day, sc, every other day. The course of treatment is 10 injections.

For the treatment of anogenital warts, the daily dose is 100,000 IU. The drug is administered 1 time per day, after the cryodestruction, after a day.The course of treatment is 5 injections.

Side effect

• local soreness at the site of subcutaneous injection in the form of mild pain of a lomiting nature (like an overtrained muscle) and hyperemia;
• development of influenza-like syndrome: headache, weakness, fever, joint pain. Slightly expressed symptoms do not require pharmacological correction. With the expressed phenomena - the docking with the help of paracetamol.

Contraindications

• pregnancy;
• autoimmune diseases;
• diabetes;
• children under 7 years of age (for intranasal use);
• individual intolerance to interferon gamma or any other component of the drug.

Application in pregnancy and lactation

Ingarone is contraindicated in pregnancy.

Use in children

The intranasal form of the drug is contraindicated in children under the age of 7 years.

special instructions

With pronounced local and general reactions, treatment should be discontinued, in case of severe side effects, corticosteroids should be used to stop them.

In the Russian Federation at the time of publication of the drug in the Directory nasal form of Ingaron was not registered.

Drug Interactions

Data on drug interactions are not provided.

Analogues of Ingarone

Ingaron does not have structural analogs for the active substance.

Analogues for the pharmacological group (interferons):

• Avonex;
• Algeron;
• Altevir;
• Alfaron;
• Alfaferon;
• Betaferon;
• Vagiphereon;
• Viferon;
• Wallferon;
• Genfaxon;
• Genferon;
• Genferon Light;
• Herpferon;
• Hyaferon;
• Grippferon;
• Inter;
• Interferal;
• Interferon alfa is a human recombinant;
• Interferon beta is a human recombinant;
• Interferon gamma recombinant human;
• Interferon leukocyte human;
• Interferon human leukocyte in suppositories;
• Interferon alfa recombinant ointment on a hydrogel-based;
• Intron A;
• Infagel;
• Inferon;
• Infibet;
• Kipferon;
• Layfferon;
• Lokferon;
• Ophthalmoferon;
• PegAtlevir;
• Pegasys;
• Peginterferon;
• Realdiron;
• EU Reaferon;
• Reaferon EU Lipint;
• Rebif;
• Ronbetal;
• Roferon A;
• SynnoWex;
• Extavia.

Similar medicines:

Other medicines: