Afrin - instructions for use, analogs, reviews and release forms (nasal spray 0.05% Moisturizing, Extro, solution Clean sea with seawater for children) for the treatment of cold in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Afrin. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Afrina in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analyzes of Afrina in the presence of existing structural analogues.Use for the treatment of the common cold, sinus inflammation (sinusitis), cleansing of the nasal passages in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Afrin - a vasoconstrictive drug for topical use, alpha-adrenostimulant. Oxymetazoline (an active substance of the drug Afrin) causes narrowing of the vessels of the mucous membranes of the nose, paranasal sinus and Eustachian tube, which leads to a decrease in their edema and alleviation of nasal breathing in allergic and / or infectious inflammatory rhinitis (runny nose).

Due to the presence in the spray of nasal auxiliary substances (cellulose microcrystalline and carmellose sodium and povidone-K29-32), the drug does not flow out of the nose and does not drain into the throat, tk. after injection into the nasal passages, the spray becomes more viscous and retained on the mucous membranes of the nose more effectively than the standard aqueous solution.

Afrin Moisturizer contains moisturizing substances (glycerol and macrogol-1450), which help to retain moisture, which helps to ensure the hydration of dry or irritated mucous membrane of the nose.

On the basis of published clinical studies, intranasal administration of an aromatic composition similar to that of the drug Afrin Extra,(also known as menthol), cineole (also known as eucalyptus) and camphor, causes a temporary sensation of cooling the nasal mucosa due to interaction with the cold trigeminal nerve receptors on the mucosal surface.

According to clinical studies, the drug begins to act for 1 minute, the effect lasts up to 12 hours.

Afrin Pure Sea A children's solution is 100% natural, sterile solution of natural sea water, rich in microelements. It is specifically designed as a safe, simple and effective tool for cleaning sensitive babies and babies from mucus, allergens, viruses and bacteria. Afrin Pure Sea a children's solution is specially adapted for small spouts of babies and children, starting from the 2nd week of life. The solution has a mild effect, gently treats even the most sensitive mucous membranes of the nose and is completely safe to use several times a day for a long time.

The solution does not contain volatile gases, which ensures a comfortable solution temperature when used.The solution does not contain preservatives and chemical impurities.

Afrin Pure Sea baby solution is also recommended for cleaning the nose before applying other types of treatment.

Composition

Oxymetazoline hydrochloride + excipients.

Sterile solution of sea water + auxiliary substances (Afrin Clear Sea).

Pharmacokinetics

When used as a nasal spray, oxymetazoline is practically not detected in the blood plasma.

Indications

symptomatic therapy of rhinitis (rhinitis) of allergic and / or infectious-inflammatory etiology;
obstruction of nasal breathing for colds, congestion and edema of the conjunctiva;
sinusitis (sinusitis);
eustachiitis;
hay fever.

Forms of release

Sprays nasal 0.05% (Afrin, Afrin Moisturizing, Afrin Extra) (sometimes mistakenly called aerosol or drops).

Spray nasal (Afrin Clear sea child, isotonic and hypertonic solutions).

Instructions for use and how to use them

Spray Afrin

Intranasal (in the nose).

Before each use, vigorously shake the bottle.

Before the first application of the nasal spray, it is necessary to "calibrate" it by pressing the spray headrepeatedly.

Adults and children over 6 years of age - 2-3 injections in each nasal passage with an interval of 10-12 hours. In adults, the frequency of application can be increased up to 3 times a day. Do not exceed the specified dose.

Spray Afrin Clear Sea child

Method of use:

Tilt the vial and press the nozzle once for a second.
Repeat this again to get the first dose of the spray.
Insert the nozzle into one nostril of the baby, turn and slightly raise the baby's head in one direction so that the solution can flow. Press on the nozzle.
Turn the baby's head to the other side and repeat the procedure for the other nostril.
Wait a few seconds and wipe the solution and mucus with a napkin or ask the child to clean his nose (blow his nose).

Side effect

In general, the drug is well tolerated, and possible side reactions are usually mild and transient (dry and burning sensation of the nasal mucosa, dry mouth and throat, sneezing).

With prolonged use - tachyphylaxis, reactive hyperemia and atrophy of the mucous membrane of the nasal cavity.

Benzalkonium chloride, which is part of the drug, can cause local skin reactions.

Systemic reactions: increased blood pressure, increased anxiety, nausea, dizziness, headache, insomnia, palpitations, sleep disturbances.

Contraindications

inflammation of the nasal mucosa without secretion;
atrophic rhinitis;
simultaneous use of MAO inhibitors (including the period of 14 days after their cancellation);
Children under 6 years of age (Afrin, Afrin Moisturizing, Afrin Extra);
children's age up to 2 weeks, including those in newborns (Afrin Pure Sea child);
pregnancy;
lactation period;
arrhythmias;
severe atherosclerosis;
arterial hypertension;
CRF;
angle-closure glaucoma;
hypersensitivity to the components of the drug;
increased sensitivity to sympathomimetic drugs.

Application in pregnancy and lactation

Afrin is contraindicated in pregnancy and lactation (breastfeeding).

Use in children

Contraindicated in children under 6 years of age (Afrin, Afrin Moisturizing, Afrin Extra). Contraindicated in children and newborns under 2 weeks of age (Afrin Clear Sea Child). Can be used in infants older than 2 weeks.

special instructions

With prolonged use (more than one week), it is possible to resume symptoms of nasal congestion.

If you need to continue treatment for more than 5 days, you should consult your doctor.

Avoid contact with the eye.

Impact on the ability to drive vehicles and manage mechanisms

The drug, if used correctly and at recommended doses, does not affect the driving of vehicles and work with mechanisms, however, in the event of such side effects as dizziness, the patient should refrain from these activities.

Drug Interactions

The drug slows the absorption of local anesthetic drugs, lengthens the time of their action.

Joint use with other vasoconstrictive drugs increases the risk of side effects.

With the simultaneous use of MAO inhibitors (including the period of 14 days after their withdrawal), maprotiline and tricyclic antidepressants - an increase in blood pressure.

Analogues of the drug Afrin

Structural analogs for the active substance:

Afrin moisturizing;
Afrin exstro;
Afrin Pure sea for children;
Wiks Active Sinex;
Nazivin;
Nazivin Sensitiv;
Nasol;
Nazol Advance;
Nasosphere;
Nesopin;
Knoxprey;
Oxymetazoline;
Oxymetazoline hydrochloride;
Fazin;
FERVEX spray from the cold.

Analogues for the pharmacological group (anticongestants):

Adrianol;
Aqua Maris;
AquaMaster;
Alergoftal;
Briisolin;
Halazolin;
Fornos;
Dr. Thais Alergol seawater;
Influrin;
Irifrin;
Cold storage;
Contact 400;
Xylen;
Xilobene;
Xylometazoline;
Ximelin;
Ximelin Eco;
Marimer;
Morenezal;
Sea water;
Nazivin;
Nazik;
Nazik for children;
Nasol;
Nasol Aqua;
Nazole Kids;
Naphazoline;
Naphthysine;
Nosoline;
Oxymetazoline;
Otrivin;
Otrivin Complex;
Pinosol;
Rinicold Bronho;
Rhinomaris;
Rinonorm;
Rhinorus;
Rhinostop;
Rinoflumacil;
Saline;
Sanorin;
Snoop;
Tysine;
Tizin Xylo;
Fatal;
Pharmazoline;
Physiodosis;
Physiomer spray nasal;
Fluimarine;
Humer 050 hypertonic nasal spray;
Eucazoline Aqua;
Evkasept;
Espazolin.

If there are no analogues of the medication for the active substance, you can go to the links below for diseases, from which the corresponding drug helps,and see the available analogues for therapeutic effects.

Used for the treatment of diseases: runny nose, conjunctivitis, eustachyte, sinusitis, nasopharyngitis, sinusitis, hay fever, allergic rhinitis, chronic pharyngitis, chronic rhinitis, chronic sinusitis