Osteogenon - instructions for use, reviews, analogs and forms of release (tablets 830 mg) drugs for the treatment of osteoporosis and accelerating the healing of bone fractures in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Osteogenon. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Osteogenon in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Osteogenon in the presence of existing structural analogues. Use to treat osteoporosis and accelerate the healing of bone fractures in adults, children, as well as in pregnancy and breast-feeding. Composition of the preparation.

Osteogenon - a preparation that influences the mineralization of bones (regulator of calcium-phosphorus metabolism).

Osteogenone contains the components necessary for the synthesis of bone tissue and has a dual effect on the metabolism of bone tissue: it stimulates osteoblasts and inhibits osteoclasts.

Calcium is contained in the preparation in the form of hydroxyapatite (in relation to phosphorus 2: 1), which contributes to its full absorption from the digestive tract. Inhibits the production of parathyroid hormone and prevents hormone-induced bone resorption. Delayed release of calcium from hydroxyapatite causes the absence of a peak of hypercalcemia.

Phosphorus, involved in the crystallization of hydroxyapatite, promotes the fixation of calcium in the bone and inhibits its excretion by the kidneys.

Ossein is an organic component of the preparation containing local regulators of bone tissue remodeling (beta-transforming growth factor, insulin-like growth factors 1 and 2, osteocalcin, collagen type 1), which activate the process of bone formation and inhibit bone resorption.

Beta-transforming growth factor stimulates the activity of osteoblasts, increases their number, promotes the production of collagen, and also inhibits the formation of osteoclast precursors.

Insulin-like growth factors 1 and 2 stimulate the synthesis of collagen and osteocalcin.

Osteocalcin promotes the crystallization of bone tissue by binding calcium.

Collagen type 1 provides the formation of bone matrix.

Composition

Ossein-hydroxyapatite compound + auxiliary substances.

Indications

• prevention and treatment of primary osteoporosis of various etiologies (premenopausal, menopausal, senile);
• prevention and treatment of secondary osteoporosis of various etiologies (due to rheumatoid arthritis, liver and kidney diseases, hyperthyroidism, hyperparathyroidism, imperfect bone formation, application of GCS, heparin, immobilization);
• correction of osteopenia and violations of phosphorus-calcium metabolism (including during pregnancy and during breastfeeding);
• acceleration of healing of bone fractures.

Forms of release

The tablets covered with a cover 830 mg.

Instructions for use and dosing regimen

Adults with osteoporosis are recommended to take 2-4 tablets 2 times a day; for other indications - 1-2 tablets per day.

The duration of treatment is determined by the patient's condition.

Side effect

• allergic reactions;
• hypercalcemia;
• hypercalciuria.

Contraindications

• severe renal insufficiency;
• hemodialysis;
• severe hypercalciuria;
• childhood;
• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

Osteogenon can be used during pregnancy and during breastfeeding after indications after a doctor's consultation.

Use in children

The drug Osteogenon is contraindicated in childhood.

special instructions

Patients who are predisposed to urolithiasis may need to adjust the dosage regimen depending on laboratory parameters.

Patients with impaired renal function should avoid prolonged use of high doses of the drug.

The composition of the drug includes only trace amounts of sodium chloride, so the use of osteogenone in patients with hypertension is acceptable.

Drug Interactions

Osteogenon slows down the absorption of iron preparations, bisphosphonates and antibiotics of the Tetracycline group, so when used simultaneously with these drugs, the interval between their intake should be at least 4 hours.

When Osteogenon is simultaneously used with vitamin D or thiazide diuretics, the doctor should assess the risk of developing hypercalcemia due to increased calcium resorption.

Analogues of the drug Osteogenon

The osteogenone has no structural analogs for the active substance. The drug contains a unique active substance in its composition.

Analogues on the curative effect (agents for the treatment of osteoporosis):

• Additive of calcium;
• Aquadetry;
• Aklast;
• Andriol;
• Arthromax;
• Bivalos;
• Bonviva;
• Bora Bora;
• Calcium vectrum;
• Veprena;
• Vitabs Calcium;
• Vitamin D3 Bon;
• Calcemin;
• Calcemin Advance;
• Calcium D3 Nycomed;
• Calcium D3 Nicomed Forte;
• Calcium Osteon;
• Kidron Willow;
• Xidifon;
• Lysite (L-Lysine);
• Methandrostenolone;
• Miakaltsik;
• OrtoOsteo;
• Ossin;
• Ostalon;
• Ostalon Calcium D;
• Osteoka solution;
• Osteoppan;
• Osteotriol;
• Osteohin;
• Resozcan;
• Retabolil;
• Sustanon 250;
• Tilcotyl;
• Tobitil;
• Tridin;
• Opsavit Calcium;
• Forosa;
• Forste;
• Fosavans;
• Fosamax;
• Ergocalciferol;
• Ergocalciferol (Vitamin D2);
• Ethal.

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