Ferlatum - instructions for use, analogs, reviews and release forms (solution and powder Fole, tablets) drugs to treat iron deficiency anemia and iron deficiency in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Ferlatum. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of experts on the use of Ferlatum in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Ferlatum in the presence of existing structural analogues. Use to treat iron deficiency anemia and iron deficiency in adults,children (including infants and newborns), as well as during pregnancy and lactation. Composition of the preparation.

Ferlatum - anti-anemic drug. Ferlatum contains iron protein succinylate, which is a complex compound, where the trivalent iron atoms are surrounded by a semisynthetic protein carrier, which prevents damage to the gastric mucosa.

The main function of iron is the transfer of oxygen to the tissues. Iron is a part of hemoglobin, myoglobin, iron-containing cytochrome enzymes, carries electrons and acts as a catalyst for oxidation, hydroxylation and other metabolic processes.

Calcium folinate in the preparation of Ferlatum Foul is the calcium salt of folic acid, which compensates for the lack of folate in the body.

Composition

Iron protein succinylate + excipients (Ferlatum).

Iron protein succinylate + Calcium folinate Pentahydrate + excipients (Ferlatum Foul).

Pharmacokinetics

In the acidic environment of the stomach, the proteins precipitate and form around the iron ions a dense protein shell, which excludes the irritating effect of iron on the gastric mucosa.

In the alkaline environment of the duodenum, the protective protein membrane dissolves and iron is released at the site of its best absorption.

In the blood, iron comes through active transport (absorption), which explains the impossibility of an overdose.

Indications

• treatment of latent and clinically pronounced iron deficiency (iron deficiency anemia) and folate;
• prevention of iron deficiency and folate during pregnancy, lactation, active growth, after prolonged bleeding, against a background of inadequate and unbalanced nutrition.

Forms of release

Solution for oral administration (Ferlatum).

Solution for oral administration + Powder for oral solution (Ferlatum Foul).

Other dosage forms, be it pills, drops or drops, do not exist.

Instructions for use and dosing regimen

Ferlatum

Ferlatum should be taken orally, before or after a meal.

Adults prescribe 15-30 ml per day (in an amount equivalent to 40-80 mg of Fe3 +) in 2 divided doses.

For children, starting from the newborn period, the drug is prescribed at 1.5 ml / kg of body weight per day (in an amount equivalent to 4 mg / kg per day of Fe3 +) in 2 divided doses.

Multiplicity of drug intake can be established by the doctor individually.

To prevent iron deficiency during pregnancy, the drug is prescribed 15 ml per day; for the treatment of latent or clinically pronounced iron deficiency - 15-30 ml per day in 2 divided doses.

After the normalization of serum iron and hemoglobin, therapy is continued for another 8-12 weeks, appointing Ferlatum in a maintenance dose.

Ferlatum Foul

Ferlatum Fole should be taken orally before or after a meal.

Adults 1-2 bottles per day in 2 divided doses (in an amount equivalent to 40-80 mg of ferric iron and 0.235-0.470 mg of calcium folinate pentahydrate) or in accordance with the recommendations of a doctor.

Children (from the neonatal period) at 1.5 ml / kg per day (in an amount equivalent to 4 mg / kg per day of ferric iron and 0.0235 mg / kg per day of folate calcium) in 2 divided doses or in accordance with the doctor's recommendations.

1 bottle (15 ml) contains: iron protein succinylate 800 mg (equivalent to 40 mg ferric iron) and 0.235 mg calcium folinate pentahydrate (equivalent to 0.185 mg folinic acid).

Pregnant for the prevention of iron deficiency anemia - 1 bottle per day.For treatment of latent or clinically pronounced iron deficiency - 1-2 vials a day in 2 divided doses.

After reaching the normal values ​​of serum iron and hemoglobin, the treatment is continued in a maintenance dose for at least 8-12 weeks.

Rules for the preparation of solution

To prepare a solution for oral administration, press forcefully onto the perforator of the dispenser cover so that the powder spills into the solution in the vial. Then vigorously shake the contents of the vial, remove the dosing lid and drink the solution from the vial.

Side effect

• the occurrence of gastrointestinal disorders that disappear when the dose is reduced or the drug is withdrawn.

Contraindications

• hemochromatosis;
• violation of iron utilization (including lead anemia, sidero-achestic anemia);
• non-iron deficiency anemia (including hemolytic anemia, megaloblastic anemia, caused by a lack of vitamin B12);
• chronic pancreatitis;
• cirrhosis of the liver;
• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

The use of Ferlatum and Ferlatum Fole is especially recommended for the prevention and treatment of iron and folate deficiency that develops during pregnancy and during breastfeeding.

Use in children

The use of Ferlatum and Ferlatum FoL is allowed starting from 0 years of life (infants and newborns) at the age-related dosages indicated above.

special instructions

The continuous period of application of the drug Ferlatum should not exceed 6 months, except for cases of chronic blood loss (including menorrhagia, hemorrhoids) and pregnancy.

Due to the possible development of allergic reactions, caution should be given to patients with intolerance to milk protein.

Ferlatum Foul contains sorbitol, so do not use the drug in patients with hereditary intolerance to fructose.

Impact on the ability to drive vehicles and manage mechanisms

The drug does not affect the employment of potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions (including driving vehicles).

Drug Interactions

With simultaneous application, no interaction of the Ferlatum Foul with other drugs was noted.

The absorption of iron can be increased by the simultaneous use of the drug Ferlatum Fall with Ascorbic acid at a dose of more than 200 mg.

Absorption of iron can be reduced with the simultaneous use of the drug Ferlatum Foul with antacids.

Chloramphenicol causes a delayed response to iron therapy.

Pharmacological interaction with the simultaneous use of the drug Ferlatum with antagonists of histamine H2 receptors is absent.

Some antitumor and antileukemic drugs (including aminopterin, Methotrexate and other pterin derivatives) exhibit the properties of folate antagonists.

Analogues of the drug Ferlatum

Structural analogs for the active substance:

• Ferlatum Foul.

Analogues on the pharmacological group (stimulators of hemopoiesis):

• Actyferrin;
• Argeferr;
• Biofer;
• Venofer;
• Vitaglutam;
• Hemofer;
• Gino Tardiferon;
• Granogen;
• Grazalva;
• Deoxynate;
• Dicarbamine;
• Iron gluconate;
• The iron fumarate;
• Iron polymaltose;
• CosmoFer;
• Leukogen;
• Leukomax;
• To the Leichest;
• Maltofer;
• Maltofer Foul;
• Mamifol;
• Monofer;
• Neostimium;
• Nucleospermate sodium;
• Panagen;
• Pentoxyl;
• Polydane;
• The Revolade;
• Recormon;
• Sorbifer Durules;
• Tardiferon;
• Fenules 100;
• Ferinzhekt;
• Fermed;
• Ferri;
• Ferrinate;
• Ferrohematogen;
• Ferrograduum;
• Ferronal;
• Ferronat;
• Ferroplex;
• Ferrostat;
• Ferrum Lek;
• Filgrastim;
• Folacin;
• Folic acid;
• Folic acid forte;
• Heferol;
• Ceruloplasmin;
• Cyanocobalamin;
• Epokrin;
• Epostim;
• Epoetin;
• Erythropoietin;
• Erythrostim.

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