Caripain - instructions for use, analogs, reviews and release forms (Ultra gel, cream or ointment, dry balm, plus) for intervertebral hernia, osteochondrosis, radiculitis in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Caripain. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Caripain in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of caripain in the presence of existing structural analogues. Use for the treatment of intervertebral hernia, osteochondrosis and radiculitis in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Caripain - effective for conservative treatment with papain-containing preparations of diseases of the musculoskeletal system, both without special physiotherapeutic procedures, and with procedures of electrophoresis and phonophoresis of appropriate dosage forms of a biologically active additive (BAA).

Papain is a monothiol cysteine ​​endoprotease, a natural plant-derived enzyme derived from the lactiferous juice of papaya fruits, selectively acting only on the cartilaginous tissues of the spine and joints. Papain stimulates the destruction of non-viable protein masses and at the same time is safe for viable tissues due to the presence of protease inhibitors in them.

Transcutol - a modern transcutaneous (transcutaneous) conductor, possessing high conductor properties, ensures the delivery of all active substances of the caripain Ultra gel through the skin deep into the tissues without destroying them. It also has the property of dispensing the active substances and their complexes introduced into the tissues.

Glucosamine refers to glycoproteins and actively participates in the construction of cartilaginous tissue and the synthesis of many other substances.Glucosamine is an aminomonosaccharide, it is based on chitin, a natural polymer that is derived from a shell of crustaceans. Glucosamine is used in the treatment of diseases of the spine and joints, as a natural metabolite as a means capable of providing protective and regenerative action against cartilage tissues. In the body it is used by chondrocytes as a starting material for the synthesis of proteoglycans and glycosaminoglycans. Glucosamine is well absorbed into the tissues of the body. In numerous studies of health-improving effects of glucosamine, its beneficial effect on the metabolism of cartilaginous tissues has been established. Glucosamine stimulation of the synthesis of proteoglycans and collagen was established, and the production of extracellular matrix components increased.

The Boswellia extract is obtained from the resin of the deciduous wood Boswellia Serrata L., the family of Burozera, contains not less than 65% of boswellic acids, incl. alpha and beta-boswellic acids. The extract of Boswellia is used as an anti-inflammatory agent (the mechanism of action is similar to that of non-steroidal anti-inflammatory drugs). Boswellia inhibits pro-inflammatory mediators, especially leukotrienes.In this case, does not reduce glycosaminoglycan synthesis, stops the destruction of cartilage and does not cause any negative effects. It also shows pronounced antiseptic, antimicrobial and sedative properties. It is widely used for inflammatory joint diseases, improves metabolism. Used to reduce pain, stiffness and inflammation of the joints with osteoarthritis and rheumatoid arthritis.

Chondroitin sulfate - consists of disaccharide residues of D-glucuronic acid and glucosaminoglucan (2-acetamido-2-deoxy-b-D-galactopyranose or N-acetylchondrosamine). It belongs to the group of chondroprotectors, it stimulates tissue regeneration, promotes water retention and restores damping functions in cartilage tissues. It has an anti-inflammatory effect, allows you to increase the mobility of joints and reduce pain. Chondroitin sulfate penetrates into the structure of the matrix of cartilaginous tissues and thus has a direct effect on metabolic processes. Promotes the synthesis and protection of collagen, which is the structural basis of all connective tissue tissue structures.

Composition

Papain + Chonroitin sulfate + Hyaluronic acid + Transcutol + Boswell extract + auxiliary substances (Ultra gel).

Papain + Glucosamine hydrochloride + Hyaluronic acid + excipients (cream).

Papain + Bromelain + Collagenase + Lysozyme + auxiliary substances (Caripain Plus).

Papain + Lysozyme + auxiliary substances (dry balm).

Indications

• osteochondrosis;
• protrusion;
• small intervertebral hernia (up to 3 mm);
• discogenic radiculitis;
• osteoarthritis;
• osteoarthritis;
• joint contractures and other diseases of the spine and joints;
• keloid scars of different origin.

Forms of release

Gel for external use (Caripain gel Ultra).

Cream for external use (sometimes mistakenly called ointment).

Lyophilized powder (caripain plus and dry balm).

Instructions for use and how to use them

Gel

The balanced composition of the active ingredients makes the application of the caripain Ultra gel effective in the routine External application without the use of physiotherapy procedures. Treatment course. One course of application is 20-30 days. If necessary, do repeat courses. Break between the courses - from 1 to 2 months.During the application of caripain heavy physical exertion on the body is not recommended.

Also, the use of caripain Ultra is practiced with complex treatment together with electrophoresis of dry balms caripain and caripain plus.

Cream

The optimum composition makes application of the caripain cream effective both with ultrasound (phonophoresis) and with the usual external application. Treatment course. One course of application is 20-30 days. If necessary, do repeat courses. Break between the courses - from 1 to 2 months. During the application of caripain heavy physical exertion on the body is not recommended.

External application of the cream is quite effective in the treatment of osteochondrosis, discogenic radiculitis, osteoarthritis, initial osteoarthritis, keloid scars of various origin, poorly healing wounds and burns. Also, the external application of the caripain cream is practiced with complex treatment together with electrophoresis of dry balms Karipain and Karipain Plus. But still, if you are going to apply caripain cream only for external use, we recommend using the caripain Ultra gel better, becauseIts gel formulation is specially designed exclusively for external use.

Caripain ultrasound (phonophoresis) significantly increases the effectiveness of treatment procedures compared to conventional external application and is used in the treatment of protrusions, small intervertebral hernias (up to 3 mm), discogenic radiculitis, articular contractures and keloid scars of various origins.

Powder Plus and dry balsam

Dry balm Caripain dry balm or caripain Plus is introduced by electrophoresis from the positive pole. Immediately before the procedure, 1 bottle of the drug diluted 10 ml of saline (or water for injection). Add 2-3 drops of Dimexide to the solution.

Treatment course - 1 course of application from 20 to 30 procedures. Allowed 1-2-day breaks between procedures.

For the treatment of osteochondrosis of the spine, cervical osteochondrosis, discogenic radiculitis, protrusions of the intervertebral disc - one course of treatment with the drug Karipain dry balm or Caripain Plus - from 20 to 30 procedures is recommended. If necessary, do repeat courses. Break between the courses - from 1 to 2 months.

Caripain Plus has been specially developed for the effective treatment of intervertebral hernias - including the size of more than 5 mm (and even more than 1 cm !!!), which distinguishes it from other papain-containing preparations. Intervertebral hernia treatment with dry balm and Karipain Plus course - from 2 to 3 courses of 20-30 procedures each (the number of courses is determined by the attending physician). Between courses the interval is from 1 to 2 months.

In the treatment of contractures, keloid scars, the preparation of caripain, the duration of the course is at the doctor's discretion.

Procedures for the electrophoresis of caripaina Plus for maximum effect is recommended to combine with the application of the caripain cream tube 50 g or caripain gel Ultra tube 30 g. Details - on the page of Complex treatment.

External application of dry balm Caripain Plus is much less effective than when passing the procedures of electrophoresis. Therefore, in the absence of the possibility of undergoing physiotherapeutic procedures, we recommend using the caripain Ultra gel for treatment.

When applying caripain, allergic reactions are possible. With increased sensitivity, manifested by severe itching, significant reddening of the skin and increased temperature, antihistamine therapy (tavegil,suprastin, claritin, diazolin, topical Hydrocortisone treatment, etc.). From the solution of caripain it is recommended to exclude Dimexide and individually pick up the current (but not less than 4 mA) and the time of the electrophoresis procedure (but not less than 10 min).

Between the 5 th and 8 th procedures, a temporary aggravation of the underlying disease is possible, which disappears after 3-5 procedures. It is important not to stop treatment!

Side effect

• allergic reactions to the components of the drug.

Contraindications

• individual intolerance of the components of balsam.

Do not use - intravenously and intramuscularly, with acute inflammatory processes in the tissues, with sequestration of disc herniation and foramenal location of the sequester. During the application of caripain heavy physical exertion on the body is not recommended.

Application in pregnancy and lactation

There is insufficient clinical data for the use of drugs of caripain in pregnant women and during lactation (lactation).

Use in children

Not used.

special instructions

Means Caripain dry balm and caripain plus can be used in any medical institution where there is an apparatus for electrophoresis (for example, "Stream-1").The method is specially adapted for convenient use in a polyclinic, a MSC, a medical center, a hospital. In addition, if necessary, apply massage, mild traction, manual therapy, anti-inflammatory drug therapy. Between courses, patients are recommended to practice in the pool.

An additional component of complex treatment is a special Medical Gymnastics, strengthening the muscles of the back, abdomen, neck, limbs, creating a "muscular corset" and stabilizing the spine, which allows the patient to more easily endure physical activity.

Drug Interactions

The drug is intended for external use, the absorption of active substances is minimal, as is the systemic effect on the body.

Analogues of the drug caripain

Structural analogues for the active ingredient do not have a drug. The drug is unique in the combination of active ingredients that make up its composition.

Analogues for the pharmacological group (funds for the treatment of intervertebral hernias):

• Actasulide;
• Amoeolin;
• Aponil;
• Aulin;
• Mesulide;
• Nyz;
• Nemux;
• Nimegesic;
• Nimesan;
• Nimesil;
• Nimesulide;
• Nimika;
• Nimulid;
• Novolide;
• Prolid;
• Sirdalud;
• Sulaydine;
• Tisaloud;
• Tizanidine;
• Tizanil;
• Fllolid.

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