Lopedium - instructions for use, reviews, analogs and formulations (tablets or capsules of 2 mg) antidiarrheal drugs for the treatment of diarrhea or diarrhea in adults, children and pregnancy. Composition

In this article, you can read the instructions for the use of antidiarrhoeal drug Lodumium. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Lopezium in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of the Lopeiium in the presence of existing structural analogs. Use to treat diarrhea or diarrhea in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Lodumium - antidiarrheal symptomatic drug.

Linking to the opioid receptors of the intestinal wall, Loperamide reduces the tone and motility of the smooth muscles of the intestine. Slows down the peristalsis and increases the transit time of intestinal contents. Increases the tone of the anal sphincter. Promotes retention of fecal masses and reduced urge to defecate.

The action comes quickly and lasts for 4-6 hours.

Composition

Loperamide hydrochloride + excipients.

Pharmacokinetics

Absorption of loperamide - 40%. Binding to plasma proteins - 97%. Does not penetrate the blood-brain barrier (BBB). It is almost completely metabolized in the liver by conjugation. It is excreted mainly with bile and urine.

Indications

• symptomatic treatment of acute and chronic diarrhea of ​​allergic, emotional, medicinal and radiation genesis;
• diarrhea with a change in diet, quality food composition, impaired absorption and metabolism;
• as an adjuvant for diarrhea of ​​infectious genesis;
• regulation of stool in patients with ileostomy.

Forms of release

Capsules 2 mg.

Tablets 2 mg.

Instructions for use and dosage

The drug should be taken orally, tablets and capsules swallowed, without chewing, squeezed 100 ml of water.

Adults with acute and chronic diarrhea are prescribed initially 4 mg, then 2 mg after each act of defecation in the case of a loose stool. The maximum daily dose is 16 mg.

Children over 6 years of age are prescribed 2 mg after each act of defecation in the case of a loose stool. The maximum daily dose is 6 mg.

After normalization of the stool or in the absence of stool for more than 12 hours, treatment should be discontinued.

Side effect

• gastralgia;
• dry mouth;
• nausea, vomiting;
• intestinal colic;
• constipation;
• intestinal obstruction;
• drowsiness or insomnia;
• dizziness;
• headache;
• skin rash.

Contraindications

• diverticulosis;
• intestinal obstruction;
• ulcerative colitis in the acute stage;
• Diarrhea on the background of acute pseudomembranous enterocolitis;
• in the form of monotherapy for dysentery and other gastrointestinal infections;
• 1 trimester of pregnancy;
• lactation period;
• children's age till 6 years;
• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

The drug is contraindicated for use in the first trimester of pregnancy and during lactation.

Use in children

Contraindicated in children under 6 years. Children over 6 years of age are prescribed 2 mg after each act of defecation in the case of a loose stool. The maximum daily dose is 6 mg.

special instructions

If there is no effect after 2 days of Lopedium, it is necessary to clarify the diagnosis and exclude the infectious genesis of diarrhea.

If the treatment develops constipation or bloating, the drug should be discarded.

In patients with impaired liver function, careful monitoring of signs of toxic CNS damage is necessary.

During the treatment period it is necessary to replenish the loss of fluid and electrolytes.

Each tablet or capsule of the Lediumum drug corresponds to 0.01 XE.

Impact on the ability to drive vehicles and manage mechanisms

In case of drowsiness or dizziness, you should refrain from driving and handling machinery.

Drug Interactions

Clinically significant interaction of loperamide with other drugs has not been established.

Analogues of medicinal product Lodumium

Structural analogs for the active substance:

• Diar;
• Diarol;
• Imodium;
• Laremide;
• Loperacap;
• Loperamide;
• Loperamide hydrochloride;
• Superylope;
• Enterobene.

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