Caffeine - instructions for use, reviews, analogs and forms of release (solution for subcutaneous administration in ampoules, tablets 100 mg sodium benzoate) drug for the treatment of pressure and spasms in adults, children and in pregnancy

In this article, you can read the instructions for using the drug Caffeine. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Caffeine in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Caffeine in the presence of existing structural analogues. Use to treat low blood pressure (hypotension),spasms and drowsiness in adults, children, as well as during pregnancy and lactation.

Caffeine - psycho-stimulating and analeptic means. Has a stimulating effect on the central nervous system, mainly on the cerebral cortex, respiratory and vasomotor centers. Increases mental and physical performance, reduces drowsiness, a sense of fatigue. Weakens the effect of drugs that depress the central nervous system. Has a pronounced effect on the cardiovascular system: increases the strength and frequency of cardiac contractions, increases blood pressure when hypotension. Has a moderate diuretic effect. Increases the secretion of the glands of the stomach.

Indications

• diseases accompanied by CNS depression, cardiovascular and respiratory system functions (including opioid analgesic poisoning, infectious diseases);
• spasms of cerebral vessels;
• decrease in mental and physical performance;
• drowsiness.

Forms of release

Solution for subcutaneous administration.

Tablets 100 mg of caffeine sodium benzoate.

Instructions for use and dosage

Enter subcutaneously or taken internally. Adults-100-200 mg 2-3 times a day; children - 25-100 mg 2-3 times a day.

Side-effectvie

• sleep disturbance;
• excitation;
• anxiety;
• with prolonged use it is possible to become addictive;
• tachycardia;
• increased blood pressure;
• arrhythmias;
• nausea, vomiting.

Contraindications

• arterial hypertension;
• organic diseases of the cardiovascular system (including pronounced atherosclerosis);
• glaucoma;
• increased excitability;
• sleep disorders;
• old age.

special instructions

Possible application in the form of mono- or as part of a combination therapy.

Drug Interactions

With simultaneous use, the effect of hypnotics and anesthetics is reduced.

With simultaneous use, it is possible to intensify the action of analgesics-antipyretics, salicylamide, naproxen.

With the simultaneous use of estrogens (hormonal contraceptives, agents for HRT), the intensity and duration of action of caffeine can be increased by inhibiting the isoenzyme CYP1A2 by estrogen.

With the simultaneous use of adenosine, caffeine reduces the increased heart rate and changes in blood pressure caused by adenosine infusion; reduces vasodilation caused by the action of adenosine.

With simultaneous use, it is possible to increase the bioavailability, rate of absorption and concentration in the blood plasma of acetylsalicylic acid.

With simultaneous use, mexiletine reduces caffeine clearance and increases its plasma concentration, apparently due to mexiletine inhibition of caffeine metabolism in the liver.

Metoxalen reduces the excretion of caffeine from the body with the possible enhancement of its effect and the development of toxic effects.

Due to the induction of microsomal enzymes of the liver under the influence of phenytoin, it simultaneously accelerates the metabolism and elimination of caffeine.

Fluconazole and Terbinafine cause a moderate increase in the concentration of caffeine in the blood plasma, Ketoconazole - less pronounced.

The most pronounced increase in AUC and a decrease in clearance are observed with simultaneous use of caffeine with enoxacin, ciprofloxacin, pipemidic acid; less pronounced changes - with pefloxacin, norfloxacin, and fleroxacin.

With the simultaneous use of caffeine accelerates the absorption of ergotamine.

Analogues of the drug Caffeine

Structural analogs for the active substance:

• Dia-actactan-N;
• Caffeine is anhydrous;
• Caffeine-benzoate sodium.

Similar medicines:

Other medicines: