Klindovit - instructions for use, reviews, analogs and forms of release (gel, ointment or cream 1%) drugs for the treatment of acne, acne or acne in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Klindovit. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Klindovit in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Klindovit with available structural analogues. Use to treat acne, acne or acne in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Klindovit - antibiotic from the group of lincosamides. It is active against all strains of Propionibacterium acnes.

Inhibits the synthesis of protein in the microbial cell due to interaction with the 50S-subunits of the ribosomes.

Clindamycin phosphate is not active, but after application on the skin it is rapidly hydrolyzed by phosphatases in the ducts of the sebaceous glands with the formation of clindamycin, which has antibacterial activity. After application to the skin, the amount of free fatty acids on the skin surface decreases from about 14% to 2%.

Composition

Clindamycin (in the form of phosphate) + auxiliary substances.

Pharmacokinetics

After application to the skin, Clindamycin rapidly accumulates in comedones in acne patients, where it exhibits antibacterial activity. After application of 1% clindamycin phosphate gel to the skin in serum and urine, very low concentrations of clindamycin are detected.

Indications

• treatment of acne (acne vulgaris, acne or acne).

Forms of release

Gel for external use 1% (sometimes mistakenly called cream or ointment).

Instructions for use and how to use them

The drug is used externally. The gel is applied a thin layer on the affected part of the previously cleaned and dried skin 2-3 times a day.

To obtain a therapeutic effect, treatment should be continued for 6-8 weeks, and if necessary, continue for up to 6 months.

Side effect

• possibly irritation (at the site of application), burning, itching, dry skin;
• erythema;
• peeling;
• increased sebum secretion;
• contact dermatitis;
• pseudomembranous enterocolitis (the probability of development is available with systemic absorption of clindamycin).

Contraindications

• Crohn's disease;
• ulcerative colitis (including in the anamnesis);
• pseudomembranous colitis (including in the anamnesis);
• increased sensitivity to clindamycin or lincomycin.

Application in pregnancy and lactation

Clindovitis can be used topically during pregnancy if the intended benefit of therapy for the mother exceeds the potential risk to the fetus.

If it is necessary to use lactation during breastfeeding, it is recommended to stop breastfeeding.

Use in children

Caution should be used in patients under 12 years of age (safety and efficacy data are not available).

special instructions

In use, avoid contact with the eyes and mouth, and after washing, wash hands.

Caution should be used in patients under 12 years of age (safety and efficacy data are not available), during lactation (breastfeeding), as well as in patients predisposed to developing allergic reactions and with simultaneous intake of muscle relaxants.

Drug Interactions

Clindamycin and Erythromycin are antagonists, so the simultaneous administration of these antibiotics is not recommended.

There is cross-resistance between clindamycin and lincomycin.

Clindamycin can enhance the action of muscle relaxants, disrupting neuromuscular transmission.

Analogues of the drug Klindovit

Structural analogs for the active substance:

• Dalacin;
• Mirror;
• Klimitsin;
• Clindamycin;
• Klindatop;
• Clindefer;
• Clindacine;
• Clindes.

Analogues on the curative effect (remedies for acne treatment):

• Aquazan;
• Acnekutan;
• Androkur;
• Arthromax;
• Basiron AC;
• Bellune 35;
• Betula Charm;
• Betusil;
• Biseptol;
• Wilprafen;
• Delex Acne gel from acne;
• Deleks Acne cleansing lotion;
• Jess;
• Jess Plus;
• Diane 35;
• Dimephosphone;
• Doxal;
• Doxycycline;
• Genetten;
• Mirror;
• Zinerit;
• Zitrolid forte;
• Curious;
• Kutis compositum;
• Purge of Puree;
• Metronidazole;
• Microfolline;
• Monoclin;
• Piolizin;
• Proderm;
• Retinoic ointment;
• Roaccutane;
• Rosamet;
• Roxithromycin Lek;
• Silhouettes;
• Skinoren;
• Streptonitol;
• Sudokrem;
• Chloe;
• Zinctal;
• Cytale;
• Eplan;
• Erica 35;
• Unidox Solutab;
• Yarina Plus.

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