Indinol - instructions for use, analogs, reviews and release forms (capsules 200 mg Forto, Epigallate and 300 mg, tablets 416 mg) drugs for the treatment of mastitis, fibroids, endometriosis in adults, children and pregnancy. Composition
In this article, you can read the instructions for using the drug Indinol. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Indinol in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Indinol in the presence of existing structural analogues. Use for the treatment of mastopathy, fibroids, endometriosis in adults, children, as well as during pregnancy and lactation. Composition of the preparation.
Indinol - is a universal corrector of pathological hyperplastic processes in the organs and tissues of the female reproductive system (mammary gland, endometrium, myometrium, cervix, ovaries). Normalizes the balance of estrogens in the body and suppresses their negative stimulating effect, and also blocks other (hormone-independent) mechanisms that activate pathological cell growth in the tissues of the breast and uterus. Has the ability to cause selective death of transformed cells with abnormally high proliferative activity.
Indinol Forto is a universal corrector of pathological hyperplastic processes in the tissues of the breast. The therapeutic effect of Indinol Forto is based on its antiestrogenic and antiproliferative action. The main property of the drug Indinol Forto is its ability to cause selective death of breast cells with abnormally high proliferative activity.
Active substances Epigallata have multiple etiopathogenetic effects on the hyperplastic processes of the reproductive system.Inhibit the abnormal growth and division of cells in organs and tissues of the female reproductive system, due to non-hormonal stimuli. Reduce the invasive activity of endometrial cells, as well as cause selective death (apoptosis) of cells with increased proliferative activity. Epigallate has a pronounced anti-angiogenic effect (suppresses the pathological growth of new vessels), and so on. prevents the growth of tumors. It is an effective anti-inflammatory agent, suppressing the activity of COX-2, PG and the synthesis of pro-inflammatory cytokines, and in addition, enhances the action of antibiotics (tetracyclines, beta-lactams) and increases the sensitivity of resistant microorganisms to the action of antibacterial agents. Has a pronounced antioxidant effect, neutralizing the formation of free radicals.
Composition
Indolucarbinol + auxiliary substances.
Indications
- for prophylaxis and as part of the complex treatment of fibrocystic mastopathy, as well as for the correction of the functional state of the mammary glands caused by this pathology;
- in combination with dietary supplements Epigallate in the complex treatment of endometriosis, adenomyosis, uterine fibroids and endometrial hyperplasia without atypia,and to prevent the recurrence of these diseases after surgical treatment;
- in the complex treatment of diseases of the genital sphere in women associated with the human papillomavirus, cervical dysplasia (intraepithelial cervical neoplasia), anogenital condylomatosis.
Forms of release
Capsules 300 mg.
Capsules 200 mg of Forto and Epigallate (sometimes mistakenly called Indinol Forte, but such a dosage form does not exist, probably, there is in view the BAA of the company Evalar-Indole Forte).
Tablets 416 mg.
There are no other dosage forms, be it drips or ampoules for injections.
Instructions for use and dosing regimen
Capsules 300 mg
Inside. Women suffering from fibrocystic mastopathy, Indinol is recommended to take inside, 1 capsule a day during meals for 2-3 weeks.
As part of combination therapy (endometrial hyperplasia without atypia, endometriosis, adenomyosis, uterine fibroids), it is recommended to take indinol in combination with a supplements of Epigallate (1 capsule + 1 capsule) during meals for 2-3 weeks.
Perhaps more prolonged use on the recommendation of a doctor.
In diseases of the genital area associated with the human papillomavirus, Indinol is recommended to take 1 capsule 1 time per day in combination with immunomodulating medications used as a standard treatment for these diseases. In this case, the course of treatment must be passed to both sexual partners.
Forto Capsules
Inside, 2 times a day for 200 mg.
The daily dose of the drug is 400 mg. Capsules are taken before meals.
Duration of treatment 6 months.
Side effect
- disorders of the menstrual cycle in the form of lengthening or shortening;
- pain in epigastrium;
- increased concentrations of thyroid-stimulating and follicle-stimulating hormones, prolactin and estradiol;
- decreased creatinine concentration;
- eosinophilia;
- decrease in body weight.
If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.
Contraindications
- hypersensitivity to the components of the drug;
- hereditary intolerance to galactose;
- deficiency of lactase;
- glucose-galactose malabsorption;
- pregnancy;
- breast-feeding;
- children and adolescence up to 18 years.
Application in pregnancy and lactation
Contraindicated the use of the drug Indinol during pregnancy and lactation.
Use in children
Contraindicated in children and adolescents under the age of 18 years.
special instructions
According to preclinical and clinical studies, Indinol is well tolerated, not having therapeutic side effects.
Impact on the ability to drive vehicles and manage mechanisms
Based on the characteristics of pharmacodynamics and the profile of undesirable effects, it is unlikely that Indin has an impact on the ability to drive vehicles and work with machinery.
Drug Interactions
Taking into account the influence of indolcarbinol on the activity of cytochrome P450 isoenzymes, caution should be exercised when combined with medicaments with cytochrome P450 isoenzymes involved in the metabolism (indirect anticoagulants, glucocorticosteroids, oral hypoglycemic agents, antiarrhythmic, antiepileptic, digitalis preparations, sex hormone preparations) to. may need to adjust their dose.
Analogues of the drug Indinol
Structural analogs for the active substance:
- Indinol Forto;
- Indinol + Epigallate;
- Intrinol.
Analogues on the curative effect (remedies for mastodynia):
- Agnukaston;
- Bromocriptine;
- Mastodinone;
- Norkolut;
- Projest;
- Cyclodinone.
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