Fanigan - instructions for use, analogs, reviews and release forms (tablets, fast gel or ointment) anesthetic medication to treat bruises, sprains, headaches, dental and joint pain in adults, children and during pregnancy. Composition

In this article, you can read the instructions for using the drug Fanigan. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of experts on the use of Fanigan in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Fanigan in the presence of existing structural analogs.Use to treat bruises, sprains, headaches, dental and joint pain in adults, children, as well as during pregnancy and lactation. Composition of an anesthetic and anti-inflammatory drug.

Fanigan - is a combined drug, it includes Diclofenac and paracetamol, which cause a pronounced anti-inflammatory, analgesic, and antipyretic effect. The action of diclofenac is based on the inhibition of the enzyme for the synthesis of prostaglandins of cyclooxygenase, which provides analgesic and antipyretic effect. At the used dose, it does not inhibit the synthesis of proteoglycans of the cartilaginous tissue. The analgesic and antipyretic effect of Paracetamol is due to its effect on the hypothalamus, in particular on the pain center and the center of thermoregulation of the brain. In rheumatic diseases, Fanigan reduces pain in the joints, morning stiffness and swelling due to anti-inflammatory and analgesic effects. In the postoperative and post-traumatic periods, he anesthetizes, reduces the swelling of the postoperative wound. Fanigan is good at pain syndrome associated with primary dysmenorrhea and migraine attacks.

Composition

Paracetamol + Diclofenac sodium + excipients (tablets).

Diclofenac diethylamine + Menthol + Methylsalicylate + auxiliary substances (Fast gel).

Pharmacokinetics

After oral administration of Fanigan, the constituent components are rapidly absorbed. The intake of food does not affect the absorption of the drug. The concentration of active substance in the blood plasma is directly proportional to the dose of the drug, the maximum level comes in one - an hour and a half after administration. Diclofenac almost 100% binds to blood plasma proteins, it also enters the synovial fluid, where its maximum concentration comes 120-240 minutes later than in the blood serum. Excretion of diclofenac occurs with urine (60%), and the rest - with bile and calves. Metabolism of paracetamol occurs in the liver, from the body it is excreted almost completely with urine.

Indications

• rheumatoid arthritis;
• arthrosis
• ankylosing spondylitis (Bekhterev's disease);
• rheumatic damage of soft tissues (tendovaginitis, bursitis, myositis);
• acute gouty, infectious, psoriatic and post-traumatic arthritis;
• degenerative joint diseases (osteoarthrosis of large and small joints);
• osteocondritis of the spine;
• myalgia, neuralgia, sciatica;
• injuries (bruises, sprains, muscles and tendons);
• pain in muscles and joints, caused by severe physical exertion;
• headache, toothache, joint pain;
• neuralgia;
• sciatica;
• with diseases of the ENT - organs (otitis media, tonsillitis, pharyngitis);
• with severe attacks of migraine, renal colic, hepatic colic;
• pain syndrome in the muscles and joints, which arose after heavy physical exertion.

Forms of release

Pills.

Gel Fanigan Fast (sometimes mistakenly called ointment).

Instructions for use and how to use them

Fast gel

Depending on the area of ​​the painful area, 2-4 g of gel (stripe 4-8 cm) is applied a thin layer on the skin and easily rubbed 2-3 times a day. The average daily dose is 10 g of gel (contains 100 mg of diclofenac sodium).

Apply the drug on intact skin, avoid contact with eyes and mucous membranes. Do not apply gel to open wounds.

The duration of treatment should not exceed 10 days.

Pills

The dosage of the drug is individual and depends on the age, disease and its course, the effect of the drug and its tolerance to the patient.At the initial stage of therapy, adults and adolescents over 14 years of age are prescribed two to three tablets per day. If the symptoms of the disease are mild, and also in the case of long-term use of the drug, usually two tablets are sufficient with an interval of 12 hours. The maximum daily dosage is 3 tablets.

Treatment lasts five to seven days.

Side effect

• nausea, vomiting;
• constipation, diarrhea;
• exacerbation of ulcerative colitis;
• headache;
• dizziness;
• drowsiness;
• irritability;
• insomnia;
• disturbance of sensation, sight and taste sensations;
• dry skin;
• skin rash;
• hives;
• bullous rash;
• eczema;
• Stephen-Johnson syndrome;
• Lyell's syndrome (toxic epidermal necrolysis);
• hepatitis;
• tachycardia;
• increased blood pressure;
• pain behind the sternum;
• bronchospasm;
• anaphylactic reaction;
• vasculitis;
• pneumonitis;
• acute renal insufficiency;
• proteinuria, hematuria;
• nephrotic syndrome;
• leukocytopenia, thrombocytopenia, hemolytic and aplastic anemia, agranulocytosis.

Contraindications

• increased sensitivity to diclofenac and other components of the drug;
• damage to the epidermis, open wounds in the area of ​​application;
• asthmatic status with acetylsalicylic acid;
• violations of hematopoiesis of unknown etiology;
• peptic ulcer of the stomach and duodenum in the stage of exacerbation;
• deficiency of glucose-6-phosphate dehydrogenase;
• lesions of the liver and kidneys in the stage of decompensation;
• 3 trimester of pregnancy (for gel) and any period of pregnancy (for tablets);
• lactation;
• children under 12 years (for the gel) and up to 14 years (for tablets).

Application in pregnancy and lactation

Reception of preparation Fanigan in tablets at pregnancy and during feeding by a breast is forbidden. Like other non-steroidal anti-inflammatory drugs (NSAIDs), Fanigan can lead to premature closure of the Botallov duct, the onset of pulmonary hypertension, oliguria, and lack of hydration. Increased risk of uterine bleeding, atony of the uterus and peripheral edema.

The use of Fanigan gel Fast is contraindicated in the third trimester of pregnancy.

Use in children

Gel is contraindicated in children under 12 years of age (there is insufficient experience of topical application of the drug in children).

Tablets are contraindicated for children under the age of 14 years.

special instructions

In the case of appointing Fanigan, patients with gastric and intestinal pathology, as well as a history of peptic ulcer disease, patients with Crohn's disease or ulcerative colitis need careful medical supervision. When taking Fanigan, an increase in the activity of liver enzymes is possible, so in the case of prolonged treatment, continuous monitoring of liver function is indicated. If the activity of liver enzymes increases or there are other symptoms indicative of liver disease, then the drug must be canceled. Fanigan can also cause attacks of hepatic porphyria, so such patients are appointed with caution.

In providing normal renal blood flow, an important role belongs to prostaglandins, so patients with kidney or heart disease, elderly patients, patients who take diuretics, and those who can be suspected of a significant decrease in BCC (eg, postoperative patients) are especially cautious. Abolition of the drug leads to the normalization of kidney function.

Fanigan may also inhibit platelet aggregation during the treatment period, so continuous monitoring of the hemostatic system is necessary during the administration of the drug.

In patients in old age, weakened, and also having a small weight, Fanigan should be prescribed in the minimum effective dose.

Fanigan, due to its properties, can mask the symptoms of infectious diseases.

Patients whose activities require increased attention should be aware of the possibility of dizziness and caution.

Drug Interactions

Fanigan increases the content of lithium and Digoxin in the blood serum. It reduces the activity of diuretics, so you should constantly monitor the level of potassium blood while prescribing it with potassium-sparing diuretics.

The appointment of Fanigan and NSAIDs simultaneously increases the likelihood of side effects, and constant monitoring of the peripheral blood picture is also necessary.

With the simultaneous appointment of Fanigan and anticoagulants, the risk of bleeding increases, so regular monitoring of blood clotting is necessary.

Fanigan increases the concentration of Methotrexate in the blood plasma.It also increases the nephrotoxic effect of cyclosporine.

Analogues of the drug Fanigan

Structural analogs for the active substance:

• Dolaren.

Analogues on the curative effect (drugs for the treatment of toothache):

• Actasulide;
• Analgin;
• Aspirin;
• Aertal;
• Brustan;
• Brufen SR;
• Grippostad;
• Dexalgin;
• Diclofenac;
• Ibuklin;
• Ibuprofen;
• Ibufen;
• Indomethacin;
• Caffetin;
• Ketorol;
• MIG 400;
• Nyz;
• Naklofen;
• Nalgezin;
• Nemux;
• Nimesil;
• Nimesulide;
• Nurofen;
• Nurofen for children;
• Nurofen fort;
• Oxadol;
• Paracetamol;
• Pentalgin;
• Pliwalgin;
• Sedalgin Neo;
• Tylenol;
• Tempalgin;
• Upsarin of the UPSA;
• Faspik;
• Flamax;
• Hyrumat;
• Cefexon;
• Citrapar;
• Citramon;
• Excedrin;
• Yunispaz.

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