Minolexin - instructions for use, reviews, analogs and forms of release (capsules or tablets 50 mg and 100 mg) antibiotic medicines for the treatment of acne or acne, sore throats, pneumonia in adults, children and in pregnancy
In this article, you can read the instructions for using the drug Minolexin. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Minolexin in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Minolexin in the presence of existing structural analogues. Use of antibiotic for the treatment of acne or acne, sore throat, pneumonia in adults, children, as well as during pregnancy and lactation.
Minolexin antibiotic of the Tetracycline group.It has a bacteriostatic effect by suppressing protein synthesis by reversible binding to the ribosomal subunit of 30S sensitive microorganisms.
It is active against Gram-positive bacteria: Staphyloccocus aureus (Staphylococcus aureus), Streptococcus spp. (streptococcus), Nocardia spp., Listeria spp. (listeria), Bacillus anthracis; Gram-negative bacteria: Neisseria meningitidis, Bartonella bacilliformis, Vibrio cholerae, Escherichia coli (E. coli), Klebsiella spp. (Klebsiella), Shigella spp. (shigella), Acinetobacter spp., Haemophilus spp .; anaerobic bacteria: Clostridium spp., Bacteroides spp.
Minocycline is also active against Mycobacterium spp. (incl. Mycobacterium leprae), Chlamydia spp. (chlamydia), Ureaplasma urealyticum (ureaplasma), Treponema pallidum.
Composition
Minocycline hydrochloride + excipients.
Indications
- acne (acne or acne);
- nocardiosis;
- lepra (as part of combination therapy);
- pneumonia;
- bronchitis;
- empyema of the pleura;
- angina;
- cholecystitis;
- pyelonephritis;
- intestinal infections;
- endocarditis;
- endometritis;
- prostatitis;
- syphilis;
- gonorrhea;
- brucellosis;
- rickettsiosis;
- suppurative infections of soft tissues (furuncle, carbuncle);
- osteomyelitis;
- trachoma.
Forms of release
Capsules 50 mg and 100 mg (sometimes mistakenly called tablets).
Instructions for use and dosing regimen
When administered orally, the daily intake for adults is 100-200 mg.
For children older than 8 years, the dose is 4 mg / kg, then 2 mg / kg every 12 hours.
Side effect
- vestibular disorders (dizziness, instability);
- pigmentation of the skin and mucous membranes;
- hepatotoxic effect;
- nausea, vomiting;
- candidiasis.
Contraindications
- abnormal liver function;
- children's age till 8 years;
- hypersensitivity to tetracyclines.
Application in pregnancy and lactation
Minolexin penetrates the placental barrier and is excreted in breast milk.
Do not use in the second half of pregnancy and during lactation, tk. minocycline causes a discoloration of the teeth, hypoplasia of the enamel and a violation of the growth of the bones of the skeleton of the fetus and the baby.
Use in children
Minocycline causes a discoloration of the teeth, hypoplasia of the enamel and dysplasia of the skeleton of the fetus and child, so Minolexin is not used in children under 8 years old.
special instructions
When taken with milk and dairy products, the absorption of minocycline is disturbed.
Drug Interactions
Minocycline weakens the bactericidal effect of Amoxicillin.
Minolexin weakens the bactericidal effect of benzathine benzylpenicillin (stops bacterial growth).
Increases absorption and the likelihood of development of intoxication in patients taking Digoxin, especially in those of them in which Digoxin is destroyed by the bacterial flora of the intestine.
Minocycline enhances the photosensitizing effect of Metoxalene (should not be prescribed together).
Analogues of the drug Minolexin
Structural analogs for the active substance:
- Minocycline hydrochloride.
Analogues for the pharmacological group (tetracyclines):
- Bassado;
- Vibramycin;
- Widokcin;
- Dovitsin;
- Doxal;
- Doksybeene;
- Doxilan;
- Doxycycline;
- Innolier;
- Xedocine;
- Monoclin;
- Oletaterrin;
- Rondomycin;
- Tetracycline;
- Tigacil;
- Ericycline;
- Yunidox Solutab.
Similar medicines:
Other medicines:
- Antisthene - instructions for use, reviews, analogs and form of release (20 mg tablets, prolonged action of CF 35 mg) of the drug for the treatment of coronary heart disease and other vascular disorders in adults, children and pregnancy. Alcohol
- Zinforo - instructions for use, analogs, reviews and release forms (injections in ampoules for injections, infusions) of the antibiotic drug for the treatment of community-acquired pneumonia and other infections in adults, children and in pregnancy
- Letrozole - instructions for use, analogs, reviews and release forms (tablets 2.5 mg) drugs for the treatment of malignant tumors and breast cancer in women, including during pregnancy. Composition